1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O²,O³-bis-(4-methyl-benzoyl)-L_g-tartrate (1:1)

Base Information

• Chemical Name: 1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O²,O³-bis-(4-methyl-benzoyl)-L_g-tartrate (1:1)
• CAS No.: 33033-87-3
• Molecular Formula: C₁₈H₁₉NO₄*C₂₀H₁₈O₈
• Molecular Weight: 699.711
• Mol file: 33033-87-3.mol

Synonyms:

Chemical Property of 1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O²,O³-bis-(4-methyl-benzoyl)-L_g-tartrate (1:1)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O²,O³-bis-(4-methyl-benzoyl)-L_g-tartrate (1:1)

There total 2 articles about 1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O²,O³-bis-(4-methyl-benzoyl)-L_g-tartrate (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride (23840-28-0) → 1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O2,O3-bis-(4-methyl-benzoyl)-Lg-tartrate (1:1) (33033-87-3)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄ / methanol / Ambient temperature

2: ethyl acetate

With sodium tetrahydroborate; In methanol; ethyl acetate;

DOI:10.1016/S0040-4020(01)90744-6

Reference yield:

(rac)-1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline (32886-66-1) + Di-p-toluoyl-L-tartaric acid (32634-66-5) → 1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline; O2,O3-bis-(4-methyl-benzoyl)-Lg-tartrate (1:1) (33033-87-3)

Guidance literature:

In ethyl acetate;

DOI:10.1016/S0040-4020(01)90744-6

upstream raw materials:

(rac)-1-benzo[1,3]dioxol-5-yl-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline

Di-p-toluoyl-L-tartaric acid

1-(1,3-benzodioxol-5-yl)-6,7-dimethoxy-3,4-dihydroisoquinoline hydrochloride