9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene

Base Information

Chemical Name:9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene
CAS No.:187754-48-9
Molecular Formula:C₂₁H₁₇BrO
Molecular Weight:365.269
Hs Code.:
DSSTox Substance ID:DTXSID101245183

Synonyms:9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene;DTXSID101245183;187754-48-9

Suppliers and Price of 9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene

Chemical Property:

XLogP3:6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:364.04628
Heavy Atom Count:23
Complexity:375

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)Br)CC2C3=CC=CC=C3C4=CC=CC=C24

Technology Process of 9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene

There total 1 articles about 9-[(2-Bromo-5-methoxyphenyl)methyl]-9H-fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86-73-7
9H-fluorene

: 19614-12-1
2-bromo-5-methoxybenzyl bromide

: 187754-48-9
9-(2-Bromo-5-methoxy-benzyl)-9H-fluorene

Guidance literature:: With n-butyllithium; Multistep reaction; 1.) THF, -78 deg C, 3 h, 2.) THF;
DOI:10.1021/jo962059n

Reference yield:

: 187754-48-9
9-(2-Bromo-5-methoxy-benzyl)-9H-fluorene

: 9,9-Bis-(3-methoxy-benzyl)-9H-fluorene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 23 deg C, 2.) DMF

2: 35 percent / K₂CO₃, Pd(OAc)2, Bu₄NBr / dimethylformamide / 36 h / 120 °C

With palladium diacetate; tetrabutylammomium bromide; sodium hydride; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/jo962059n

Reference yield:

: 187754-48-9
9-(2-Bromo-5-methoxy-benzyl)-9H-fluorene

: 7b-(2-Bromo-5-methoxy-benzyl)-10-nitro-7b,8-dihydro-benzo[e]acephenanthrylene

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 23 deg C, 2.) DMF

2: 67 percent / K₂CO₃, Pd(OAc)2, BnMe₃NBr / dimethylformamide / 24 h / 70 °C

With palladium diacetate; trimethylbenzylammonium bromide; sodium hydride; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/jo962059n