iron(III) protoporphyrin IX dimethyl ester chloride

Base Information

• Chemical Name: iron(III) protoporphyrin IX dimethyl ester chloride
• CAS No.: 49859-41-8
• Molecular Formula: C₃₆H₃₆ClFeN₄O₄
• Molecular Weight: 680.006
• Mol file: 49859-41-8.mol

Synonyms:

Chemical Property of iron(III) protoporphyrin IX dimethyl ester chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of iron(III) protoporphyrin IX dimethyl ester chloride

There total 2 articles about iron(III) protoporphyrin IX dimethyl ester chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

protoporphyrine IX dimethylester + iron(II) chloride → iron(III) protoporphyrin IX dimethyl ester chloride (49859-41-8,15741-03-4)

Guidance literature:

In methanol; chloroform; Heating FeCl2 with the ligand in CHCl3-MeOH (1:1) in an inert atmosphere;

DOI:10.1023/A:1012372010323

Reference yield:

hydrated iron(III)chloride + protoporphyrin IX dimethyl ester (5522-66-7,6164-53-0) → iron(III) protoporphyrin IX dimethyl ester chloride (49859-41-8,15741-03-4)

Guidance literature:

In N,N-dimethyl-formamide; Reflux;

DOI:10.1002/cjoc.201200581

Reference yield: 75.8%

iron(III) protoporphyrin IX dimethyl ester chloride (49859-41-8,15741-03-4) + [(p-methylphenyl)sulfonylmethyl]isonitrile (38622-91-2,36635-61-7) → bis(tosylmethyl isocyanide)iron(II) protoporphyrin IX dimethyl ester (122056-85-3)

Guidance literature:

With Na₂S₂O₄; In pyridine; dichloromethane; water; addn. of aq. Na2S2O4 to Fe-complex in pyridine, pouring of mixt. into ice water, extraction (CH2Cl2), washing of org. phase (water), drying over Na2SO4, filtn., evapn., dissoln. (CH2Cl2), addn. of tosylate; chromy. (CH2Cl2/MeOH), recrystn. (benzene/light petroleum ether 1:1); elem. anal.;

DOI:10.1246/bcsj.61.3539

upstream raw materials:

protoporphyrin IX dimethyl ester

Downstream raw materials:

bis(tosylmethyl isocyanide)iron(II) protoporphyrin IX dimethyl ester