(R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

Base Information

• Chemical Name: (R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
• CAS No.: 1172617-27-4
• Molecular Formula: C₂₁H₁₉ClN₄O₃S
• Molecular Weight: 442.926
• Mol file: 1172617-27-4.mol

Synonyms:

Chemical Property of (R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine

There total 2 articles about (R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H15BrO4 (1176406-09-9) + 4-amino-5-(2-chlorophenyl)-2,4-dihydro-3H[1,2,4]triazole-3-thione (13229-02-2) → (R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (1172617-27-4)

Guidance literature:

In ethanol; at 105 ℃; for 4h; Inert atmosphere; Sealed tube;

DOI:10.1016/j.bmcl.2009.01.057

Reference yield:

→ (R)-3-(2-chlorophenyl)-6-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (1172617-27-4)

Guidance literature:

upstream raw materials:

C₁₃H₁₅BrO₄

4-amino-5-(2-chlorophenyl)-2,4-dihydro-3H[1,2,4]triazole-3-thione