3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one

Base Information

Chemical Name:3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one
CAS No.:17792-10-8
Molecular Formula:C₁₉H₂₃NO₃
Molecular Weight:313.397
Hs Code.:
NSC Number:113786
DSSTox Substance ID:DTXSID20419054
ChEMBL ID:CHEMBL1411083

Synonyms:17792-10-8;BAS 05154574;3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one;MLS000123829;SMR000124401;3-hydroxy-4-(piperidin-1-ylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one;NSC113786;Oprea1_729896;Oprea1_738824;SCHEMBL4713197;CHEMBL1411083;BDBM51618;cid_5381220;DTXSID20419054;HMS2501O18;MFCD02336900;STL455522;3-hydroxy-4-(piperidin-1-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one;AKOS000535281;NSC-113786;3-hydroxy-4-(piperidinomethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one;3-hydroxy-4-piperidinomethyl-7,8,9,10-tetrahydro-6h-benzo[c]chromen-6-one;3-hydroxy-4-(1-piperidinylmethyl)-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-6-one;3-oxidanyl-4-(piperidin-1-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

Suppliers and Price of 3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one

Chemical Property:

Vapor Pressure:1.87E-11mmHg at 25°C
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:313.16779360
Heavy Atom Count:23
Complexity:495

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)CC2=C(C=CC3=C2OC(=O)C4=C3CCCC4)O

Technology Process of 3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one

There total 4 articles about 3-Hydroxy-4-piperidin-1-ylmethyl-7,8,9,10-tetrahydro-benzo[c]chromen-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 880-09-1
di(N-piperidinyl)methane

: 3722-44-9
3-hydroxy-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

: 17792-10-8
3-hydroxy-4-piperidinomethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one

Guidance literature:: In 1,4-dioxane; at 100 ℃;
DOI:10.1023/A:1022674318345

Reference yield:

: 1655-07-8
ethyl 2-oxocyclohexane carboxylate

: 17792-10-8
3-hydroxy-4-piperidinomethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / conc. H₂SO₄ / ethanol / 0 - 20 °C

2: 76 percent / dioxane / 100 °C

With sulfuric acid; In 1,4-dioxane; ethanol; 1: Pechmann condensation / 2: Mannich reaction;
DOI:10.1023/A:1022674318345

Reference yield:

: 108-46-3
recorcinol

: 17792-10-8
3-hydroxy-4-piperidinomethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / conc. H₂SO₄ / ethanol / 0 - 20 °C

2: 76 percent / dioxane / 100 °C

With sulfuric acid; In 1,4-dioxane; ethanol; 1: Pechmann condensation / 2: Mannich reaction;
DOI:10.1023/A:1022674318345