C₄₂H₃₅F₃N₄O₂

Base Information

Chemical Name:C₄₂H₃₅F₃N₄O₂
CAS No.:1629023-87-5
Molecular Formula:C₄₂H₃₅F₃N₄O₂
Molecular Weight:684.761
Hs Code.:

C<sub>42</sub>H<sub>35</sub>F<sub>3</sub>N<sub>4</sub>O<sub>2</sub>

Synonyms:

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Chemical Property of C₄₂H₃₅F₃N₄O₂

Chemical Property:

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Technology Process of C₄₂H₃₅F₃N₄O₂

There total 12 articles about C₄₂H₃₅F₃N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620327-60-7
C₃₂H₂₉BF₃N₃O₂

: 1629023-82-0
C₁₆H₁₈BrNO₂

: 1629023-87-5
C₄₂H₃₅F₃N₄O₂

Guidance literature:: With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; water; at 20 ℃; for 2.5h;
DOI:10.1016/j.bmcl.2014.05.082

Reference yield:

: 1160502-31-7
4-iodo-3-(trifluoromethyl)-1-tritylpyrazolo[5,4-b]pyridine

: 1629023-87-5
C₄₂H₃₅F₃N₄O₂

Guidance literature:: Multi-step reaction with 2 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / N,N-dimethyl-formamide / 14 h / 105 °C

2: potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 2.5 h / 20 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium acetate; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; water; N,N-dimethyl-formamide; 1: |Suzuki Coupling / 2: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2014.05.082

Reference yield:

: 1435-51-4
1,3-dibromo-5-fluorobenzene

: 1629023-87-5
C₄₂H₃₅F₃N₄O₂

Guidance literature:: Multi-step reaction with 7 steps

1: sodium hydride / 1-methyl-pyrrolidin-2-one / 24 h / 120 °C

2: lithium chloride / dimethyl sulfoxide; water / 3 h / 165 °C

3: tetrabutylammomium bromide; sodium hydroxide / toluene; water / 16 h / 20 °C

4: copper(l) cyanide; TurboGrignard / tetrahydrofuran / 1 h / 0 - 20 °C

5: osmium(VIII) oxide; 4-methylmorpholine N-oxide / water; acetone / 16 h / 20 °C

6: toluene-4-sulfonic acid / water; acetone / 16 h / 20 °C

7: potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate / tetrahydrofuran; water / 2.5 h / 20 °C

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; osmium(VIII) oxide; TurboGrignard; tetrabutylammomium bromide; copper(l) cyanide; sodium hydride; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; lithium chloride; sodium hydroxide; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; water; dimethyl sulfoxide; acetone; toluene; 2: |Krapcho Dealkoxycarbonylation / 7: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2014.05.082