Technology Process of C17H18FNO2
There total 5 articles about C17H18FNO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: thionyl chloride / 12 h / 0 - 20 °C
2: hydrogen / methanol / 12 h / 20 °C
With
thionyl chloride; hydrogen;
In
methanol;
DOI:10.1039/c2ob26950c
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium / tetrahydrofuran
1.2: 2 h / -78 °C / Inert atmosphere
2.1: (S,E)-N-benzhydryl-1-(N,N'-dicyclohexylcarbamimidoyl)pyrrolidine-2-carboxamide / toluene / 12 h / 0 °C / Inert atmosphere; Molecular sieve
2.2: 8 h / 0 °C / Inert atmosphere; Molecular sieve
3.1: tetrabutyl ammonium fluoride; dihydrogen peroxide / tetrahydrofuran / 2 h / 20 °C
4.1: thionyl chloride / 12 h / 0 - 20 °C
5.1: hydrogen / methanol / 12 h / 20 °C
With
thionyl chloride; (S,E)-N-benzhydryl-1-(N,N'-dicyclohexylcarbamimidoyl)pyrrolidine-2-carboxamide; tetrabutyl ammonium fluoride; hydrogen; dihydrogen peroxide; lithium;
In
tetrahydrofuran; methanol; toluene;
2.1: |Michael Addition / 2.2: |Michael Addition;
DOI:10.1039/c2ob26950c