Fmoc-azidolysine

Base Information

• Chemical Name: Fmoc-azidolysine
• CAS No.: 1182847-21-7
• Molecular Formula: C₂₁H₂₂N₄O₄
• Molecular Weight: 394.43
• Mol file: 1182847-21-7.mol

Synonyms:

Chemical Property of Fmoc-azidolysine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Fmoc-azidolysine

There total 3 articles about Fmoc-azidolysine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

9-fluorenylmethoxycarbonyl-L-alanine hydrochloride (139262-23-0) → Fmoc-azidolysine (1182847-21-7)

Guidance literature:

With imidazole-1-sulfonyl azide hydrochloride; sodium hydrogencarbonate; copper(II) sulfate; In methanol; water;

DOI:10.1016/j.bmcl.2016.05.094

Reference yield: 48.0%

C6H12N4O2*ClH + N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide (82911-69-1) → Fmoc-azidolysine (1182847-21-7)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; water; at 0 - 20 ℃;

Reference yield:

6-amino-2-(9H-fluoren-9-ylmethoxycarbonyl amino)-hexanoic acid → Fmoc-azidolysine (1182847-21-7)

Guidance literature:

With imidazole-1-sulfonyl azide hydrochloride; copper(II) sulfate; In methanol; dichloromethane; water;

DOI:10.1039/c7cc05869a

upstream raw materials:

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

9-fluorenylmethoxycarbonyl-L-alanine hydrochloride