Technology Process of C18H17ClN2OS
There total 4 articles about C18H17ClN2OS which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Lawessons reagent;
In
1,4-dioxane;
at 100 ℃;
for 2h;
Reflux;
DOI:10.1021/jm400012e
- Guidance literature:
-
Multi-step reaction with 4 steps
1: copper(l) iodide; caesium carbonate; dimethylaminoacetic acid / 1,4-dioxane / 9 h / 180 °C
2: water; lithium hydroxide / tetrahydrofuran / 2 h / 20 °C
3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 5 h / 20 °C
4: Lawessons reagent / 1,4-dioxane / 2 h / 100 °C / Reflux
With
Lawessons reagent; copper(l) iodide; dimethylaminoacetic acid; water; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
1: |Ullmann Condensation;
DOI:10.1021/jm400012e
- Guidance literature:
-
Multi-step reaction with 4 steps
1: copper(l) iodide; caesium carbonate; dimethylaminoacetic acid / 1,4-dioxane / 9 h / 180 °C
2: water; lithium hydroxide / tetrahydrofuran / 2 h / 20 °C
3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 5 h / 20 °C
4: Lawessons reagent / 1,4-dioxane / 2 h / 100 °C / Reflux
With
Lawessons reagent; copper(l) iodide; dimethylaminoacetic acid; water; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
1: |Ullmann Condensation;
DOI:10.1021/jm400012e
