4-Chloroquinoline-6-carbaldehyde

Base Information

Chemical Name:4-Chloroquinoline-6-carbaldehyde
CAS No.:676256-25-0
Molecular Formula:C10H6ClNO
Molecular Weight:191.617
Hs Code.:2933499090
DSSTox Substance ID:DTXSID90697241
Wikidata:Q72459302
Mol file:676256-25-0.mol

Synonyms:4-CHLOROQUINOLINE-6-CARBALDEHYDE;676256-25-0;4-Chloroquinoline-6-carboxaldehyde;SCHEMBL732379;4-chloro-6-quinolinecarbaldehyde;DTXSID90697241;INLPDPKYJXJJMT-UHFFFAOYSA-N;4-Chloro-quinoline-6-carbaldehyde;SB67824;AS-50182;CS-0454829;FT-0718879;O11225

Suppliers and Price of 4-Chloroquinoline-6-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloroquinoline-6-carbaldehyde
100mg
$ 65.00

Crysdot
4-Chloroquinoline-6-carbaldehyde 95+%
1g
$ 465.00

Crysdot
4-Chloroquinoline-6-carbaldehyde 95+%
5g
$ 1409.00

Chemenu
4-chloroquinoline-6-carbaldehyde 95%
5g
$ 1328.00

Chemenu
4-chloroquinoline-6-carbaldehyde 95%
1g
$ 439.00

Biosynth Carbosynth
4-Chloroquinoline-6-carbaldehyde
1 g
$ 512.00

Biosynth Carbosynth
4-Chloroquinoline-6-carbaldehyde
500 mg
$ 295.00

Biosynth Carbosynth
4-Chloroquinoline-6-carbaldehyde
250 mg
$ 170.00

Biosynth Carbosynth
4-Chloroquinoline-6-carbaldehyde
100 mg
$ 85.00

Biosynth Carbosynth
4-Chloroquinoline-6-carbaldehyde
2 g
$ 891.00

Total 17 raw suppliers

Chemical Property of 4-Chloroquinoline-6-carbaldehyde

Chemical Property:

Boiling Point:332℃
PKA:2.71±0.16(Predicted)
Flash Point:154℃
PSA：29.96000
Density:1.364
LogP:2.70070
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:191.0137915
Heavy Atom Count:13
Complexity:197

Purity/Quality:

99% ^*data from raw suppliers

4-chloroquinoline-6-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC=CC(=C2C=C1C=O)Cl

Technology Process of 4-Chloroquinoline-6-carbaldehyde

There total 7 articles about 4-Chloroquinoline-6-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 916811-99-9
4-chloro-6-vinylquinoline

: 676256-25-0
4-chloroquinoline-6-carbaldehyde

Guidance literature:: With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; In 1,4-dioxane; water; tert-butyl alcohol; at 20 ℃; for 2h;

Reference yield: 25.0%

: 65340-70-7
6-bromo-4-chloroquinoline

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 676256-25-0
4-chloroquinoline-6-carbaldehyde

Guidance literature:: 6-bromo-4-chloroquinoline; With n-butyllithium; In tetrahydrofuran; hexanes; at -70 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexanes; at -70 - 20 ℃; for 2h; Product distribution / selectivity;

Reference yield:

: 65340-70-7
6-bromo-4-chloroquinoline

: 676256-25-0
4-chloroquinoline-6-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 0.33 h / 150 °C / Microwave

2: 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide / 1,4-dioxane; water; tert-butyl alcohol / 2 h / 20 °C

With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; tert-butyl alcohol;