1-(2-Chloro-4-iodopyridin-3-yl)ethanone

Base Information

Chemical Name:1-(2-Chloro-4-iodopyridin-3-yl)ethanone
CAS No.:185041-03-6
Molecular Formula:C7H5ClINO
Molecular Weight:281.48
Hs Code.:
DSSTox Substance ID:DTXSID90441529
Nikkaji Number:J1.653.227D
Wikidata:Q82258323

Synonyms:185041-03-6;1-(2-chloro-4-iodopyridin-3-yl)ethanone;Ethanone, 1-(2-chloro-4-iodo-3-pyridinyl)-;1-(2-Chloro-4-iodo-3-pyridyl)ethanone;AGN-PC-0N68LI;SCHEMBL16995132;DTXSID90441529;2-Chloro-3-acetyl-4-iodopyridine;MFCD16877188;AKOS015891970;SY282848;1-(2-Chloro-4-iodo-pyridin-3-yl)-ethanone;1-(2-chloro-4-iodopyridin-3-yl)ethan-1-one

Suppliers and Price of 1-(2-Chloro-4-iodopyridin-3-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(2-Chloro-4-iodopyridin-3-yl)ethanone

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.622
Boiling Point:310.994 °C at 760 mmHg
Flash Point:141.885 °C
Density:1.899 g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:280.91044
Heavy Atom Count:11
Complexity:165

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=CN=C1Cl)I

Technology Process of 1-(2-Chloro-4-iodopyridin-3-yl)ethanone

There total 3 articles about 1-(2-Chloro-4-iodopyridin-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 185041-02-5
1-(2-chloro-4-iodo-3-pyridyl)ethanol

: 185041-03-6
3-acetyl-2-chloro-4-iodopyridine

Guidance literature:: With pyridinium chlorochromate; In dichloromethane; for 24h; Ambient temperature;
DOI:10.1080/00397919608003845

Reference yield: 46.0%

: 108-24-7
acetic anhydride

: 78607-36-0
2-chloro-3-iodopyridine

: 185041-03-6
3-acetyl-2-chloro-4-iodopyridine

Guidance literature:: With lithium diisopropyl amide; In tetrahydrofuran; -70 deg C, 3 h, -10 deg C, 3 h;
DOI:10.1080/00397919608003845

Reference yield:

: 78607-36-0
2-chloro-3-iodopyridine

: 185041-03-6
3-acetyl-2-chloro-4-iodopyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / LDA / tetrahydrofuran / 4.5 h / -70 °C

2: 98 percent / PCC / CH₂Cl₂ / 24 h / Ambient temperature

With pyridinium chlorochromate; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane;
DOI:10.1080/00397919608003845