(2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol

Base Information

• Chemical Name: (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol
• CAS No.: 77710-87-3
• Molecular Formula: C₂₄H₄₁N₅O₉Se
• Molecular Weight: 622.578
• Mol file: 77710-87-3.mol

Synonyms:

Chemical Property of (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol

There total 3 articles about (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C62H93N5O20Se (77710-83-9) → (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol (77710-87-3)

Guidance literature:

With sodium methylate; In methanol;

DOI:10.1016/0040-4039(81)80045-7

Reference yield:

diphenyl diselenide (1666-13-3) → (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol (77710-87-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaBH₄ / 1.) dimethoxy ethane, 60 deg C

2: sodium methoxide / methanol

With sodium tetrahydroborate; sodium methylate; In methanol;

DOI:10.1016/0040-4039(81)80045-7

Reference yield:

C56H87N5O20 (64271-34-7) → (2S,3R,4S,5S,6R)-4-Amino-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-((2S,3R,4R,5S,6R)-3-amino-6-aminomethyl-4-hydroxy-5-phenylselanyl-tetrahydro-pyran-2-yloxy)-2-hydroxy-cyclohexyloxy]-6-hydroxymethyl-tetrahydro-pyran-3,5-diol (77710-87-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaBH₄ / 1.) dimethoxy ethane, 60 deg C

2: sodium methoxide / methanol

With sodium tetrahydroborate; sodium methylate; In methanol;

DOI:10.1016/0040-4039(81)80045-7

upstream raw materials:

C₆₂H₉₃N₅O₂₀Se

diphenyl diselenide

C₅₆H₈₇N₅O₂₀

Downstream raw materials:

4'-Deoxykanamycin B