3-BROMO-4,6-DINITROFLUOROBENZENE

Base Information

• Chemical Name: 3-BROMO-4,6-DINITROFLUOROBENZENE
• CAS No.: 400-91-9
• Molecular Formula: C6H2BrFN2O4
• Molecular Weight: 264.995
• Hs Code.: 2904909090
• Mol file: 400-91-9.mol

Synonyms:1-Bromo-5-fluoro-2,4-dinitrobenzene;1-Fluoro-3-bromo-4,6-dinitrobenzene;NSC 10237;

Chemical Property of 3-BROMO-4,6-DINITROFLUOROBENZENE

Chemical Property:

• Vapor Pressure: 0.00194mmHg at 25°C
• Refractive Index: 1.622
• Boiling Point: 301 °C at 760 mmHg
• Flash Point: 135.8 °C
• PSA: 91.64000
• Density: 1.984 g/cm³
• LogP: 3.45100

Purity/Quality:

99%, ^*data from raw suppliers

1-Bromo-5-fluoro-2,4-dinitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-BROMO-4,6-DINITROFLUOROBENZENE

There total 3 articles about 3-BROMO-4,6-DINITROFLUOROBENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-bromo-6-fluorobenzene-1,3-diamine (166818-71-9) → 1-bromo-3-fluoro-4,6-dinitrobenzene (400-91-9)

Guidance literature:

With dihydrogen peroxide; trifluoroacetic anhydride; In dichloromethane; for 1h; Heating;

Reference yield: 50.0%

2-bromo-4-fluoronitrobenzene (700-36-7) → 1-bromo-3-fluoro-4,6-dinitrobenzene (400-91-9)

Guidance literature:

With sulfuric acid; nitric acid; In water; at 60 ℃; for 0.5h;

DOI:10.1021/jf902320e

Reference yield:

3-fluorobromobenzene (1073-06-9) → 1-bromo-3-fluoro-4,6-dinitrobenzene (400-91-9)

Guidance literature:

With sulfuric acid; nitric acid;

upstream raw materials:

3-fluorobromobenzene

4-bromo-6-fluorobenzene-1,3-diamine

2-bromo-4-fluoronitrobenzene

Downstream raw materials:

2-(benzothiazole-2-sulfonyl)-2-(5-bromo-2,4-dinitro-phenyl)-1-phenyl-ethanone

2-(5-chloro-benzothiazole-2-sulfonyl)-2-(5-bromo-2,4-dinitro-phenyl)-1-phenyl-ethanone

C₁₀H₅FN₂O₄S

C₂₅H₂₀BrN₃O₇

Refernces

• 1、 Beugelmans, Rene,Chbani, Mohamed. "Synthesis of 5- and 6-membered heterocycles by a strategy combining SNAr and SRN1 reactions". . p. 306 - 313. Retrieved 2007/10/02.