Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate

Base Information

Chemical Name:Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate
CAS No.:80709-83-7
Molecular Formula:C₉H₈BrNO₃
Molecular Weight:258.071
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10508421
Wikidata:Q72456661
Mol file:80709-83-7.mol

Synonyms:80709-83-7;Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate;2-Bromo-4H-furo[3,2-b]pyrrole-5-carboxylic acid ethyl ester;SCHEMBL6629755;DTXSID10508421;MLBWLOCPAYJAFP-UHFFFAOYSA-N;AMY10559;MFCD13251084;AKOS015935940;AS-68177;SY103696;FT-0767599

Suppliers and Price of Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 14 raw suppliers

Chemical Property of Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate

Chemical Property:

Melting Point:120℃
Boiling Point:354.3±37.0 °C(Predicted)
PKA:13.33±0.30(Predicted)
PSA：55.23000
Density:1.662
LogP:2.70010
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:256.96876
Heavy Atom Count:14
Complexity:236

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(N1)C=C(O2)Br

Technology Process of Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate

There total 2 articles about Ethyl 2-bromo-4H-furo[3,2-b]pyrrole-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: ethyl 2-azido-3-(5-bromofuran-2-yl)acrylate

: 80709-83-7
Ethyl 2-Bromo-4H-furo<3,2-b>pyrrole-5-carboxylate

Guidance literature:: In toluene; for 2h; Inert atmosphere; Reflux;
DOI:10.1021/acs.jmedchem.7b00180

Reference yield:

: 1899-24-7
5-bromo-2-furancarboxaldehyde

: 80709-83-7
Ethyl 2-Bromo-4H-furo<3,2-b>pyrrole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / sodium ethoxide / ethanol / 1.) 30 min, 0 deg C, 2.) 60 min, 10 deg C

2: 96 percent / xylene / 0.33 h / Heating

With sodium ethanolate; In ethanol; xylene;