2-Methyl-3-nitrobenzoyl chloride

Base Information

Chemical Name:2-Methyl-3-nitrobenzoyl chloride
CAS No.:39053-41-3
Molecular Formula:C8H6ClNO3
Molecular Weight:199.594
Hs Code.:2916399090
DSSTox Substance ID:DTXSID80479952
Wikidata:Q82314355
Mol file:39053-41-3.mol

Synonyms:2-METHYL-3-NITROBENZOYL CHLORIDE;39053-41-3;2-Methyl-3-nitrobenzoylchloride;2-methyl-3-nitro-benzoyl chloride;2-methyl-3-nitrobenzoic acid chloride;SCHEMBL5727143;3-nitro-2-methylbenzoyl chloride;DTXSID80479952;UENLNPJRTOHQIC-UHFFFAOYSA-N;MFCD03840778;3-nitro-2-methylbenzoic acid chloride;AKOS009217103;CS-0279717;FT-0639517;EN300-239802;A824386;F2190-0077

Suppliers and Price of 2-Methyl-3-nitrobenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Methyl-3-nitrobenzoyl chloride 97%
1g
$ 529.00

Atlantic Research Chemicals
2-Methyl-3-nitrobenzoylchloride 95%
1gm:
$ 247.42

American Custom Chemicals Corporation
2-METHYL-3-NITROBENZOYL CHLORIDE 95.00%
1G
$ 945.95

Total 11 raw suppliers

Chemical Property of 2-Methyl-3-nitrobenzoyl chloride

Chemical Property:

Vapor Pressure:0.00259mmHg at 25°C
Melting Point:68 °C
Refractive Index:1.579
Boiling Point:286.7 °C at 760 mmHg
Flash Point:127.2 °C
PSA：62.89000
Density:1.386 g/cm³
LogP:2.80540
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:199.0036207
Heavy Atom Count:13
Complexity:226

Purity/Quality:

99%, ^*data from raw suppliers

2-Methyl-3-nitrobenzoyl chloride 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC=C1[N+](=O)[O-])C(=O)Cl
Uses 2-Methyl-3-nitrobenzoyl chloride is used as a reactant in the preparation of aroylindoles as tubulin-inhibitory antimitotic agents.

Technology Process of 2-Methyl-3-nitrobenzoyl chloride

There total 4 articles about 2-Methyl-3-nitrobenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1975-50-4
2-methyl-3-nitrobenzic acid

: 39053-41-3
2-methyl-3-nitrobenzoyl chloride

Guidance literature:: With thionyl chloride; at 60 ℃; for 25.5h; Inert atmosphere;
DOI:10.1039/c4cc09413a

Reference yield:

: 71516-35-3
2-methyl-3-nitrobenzonitrile

: 39053-41-3
2-methyl-3-nitrobenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: aqueous sulfuric acid / 150 °C

2: thionyl chloride

With thionyl chloride; sulfuric acid;
DOI:10.1002/hlca.19480310113

Reference yield:

: 118-90-1
ortho-methylbenzoic acid

: 39053-41-3
2-methyl-3-nitrobenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: absolute nitric acid / 0 °C

2: PCl₅

With phosphorus pentachloride; nitric acid;