naproxen glucuronide

Base Information

Chemical Name:naproxen glucuronide
CAS No.:41945-43-1
Molecular Formula:C20H22O9
Molecular Weight:406.389
Hs Code.:2932990090
Mol file:41945-43-1.mol

Synonyms:Naproxen Acyl--D-glucuronide;(S)-Naproxen Glucuronide;(S)-Naproxen Acyl-Beta-D-glucuronide;(+)-Naproxen glucuronide;1-[(aS)-6-Methoxy-a-methyl-2-naphthaleneacetate]-D-Glucopyranuronic Acid;

Suppliers and Price of naproxen glucuronide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-NaproxenAcyl-β-D-glucuronide
1mg
$ 205.00

Chemtos
Naproxen-acyl-1-beta-D-glucuronide
10 mg
$ 2990.00

Biosynth Carbosynth
(S)-Naproxen acyl-b-D-glucuronide
5 mg
$ 918.80

Biosynth Carbosynth
(S)-Naproxen acyl-b-D-glucuronide
1 mg
$ 262.50

Biosynth Carbosynth
(S)-Naproxen acyl-b-D-glucuronide
2 mg
$ 472.50

Biosynth Carbosynth
(S)-Naproxen acyl-b-D-glucuronide
25 mg
$ 2887.50

Biosynth Carbosynth
(S)-Naproxen acyl-b-D-glucuronide
10 mg
$ 1365.00

Apolloscientific
Naproxen-acyl-beta-D-glucuronide 98%min
2mg
$ 1005.00

Apolloscientific
Naproxen-acyl-beta-D-glucuronide 98%min
1mg
$ 544.00

American Custom Chemicals Corporation
(S)-NAPROXEN ACYL-BETA-D-GLUCURONIDE 95.00%
5MG
$ 497.82

Total 13 raw suppliers

Chemical Property of naproxen glucuronide

Chemical Property:

Vapor Pressure:2.2E-17mmHg at 25°C
Melting Point:80-82oC
Boiling Point:642.5°Cat760mmHg
PKA:2.67±0.70(Predicted)
Flash Point:227.6°C
PSA：142.75000
Density:1.48g/cm³
LogP:0.38730
Storage Temp.:-20°C Freezer, Under Inert Atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-NaproxenAcyl-β-D-glucuronide ^*data from reagent suppliers

Safty Information:

Pictogram(s): 8167705
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of naproxen glucuronide

There total 6 articles about naproxen glucuronide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 946517-36-8
C₂₇H₂₈O₉

: 41945-43-1,112828-15-6
(+)-Naproxen glucuronide

Guidance literature:: With cyclohexa-1,4-diene; palladium on activated charcoal; In tetrahydrofuran; isopropyl alcohol; for 2h; Heating;
DOI:10.1016/j.tet.2007.05.050

Reference yield: 99.0%

: benzyl 1-O-[(S)-2-(6-methoxy-2-naphthyl)propionyl]-2,3,4-tri-O-benzyl-β-D-glucopyranuronate

: 41945-43-1,112828-15-6
(+)-Naproxen glucuronide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; under 760 Torr;
DOI:10.1081/CAR-120034003

Reference yield:

: 22204-53-1
(2S)-2-(6-methoxy(2-naphthyl))propanoic acid

: 41945-43-1,112828-15-6
(+)-Naproxen glucuronide

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / HATU; N-methylmorpholine / acetonitrile / 20 °C

2: 100 percent / cyclohexa-1,4-diene / Pd-C / tetrahydrofuran; propan-2-ol / 2 h / Heating

With 4-methyl-morpholine; cyclohexa-1,4-diene; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; palladium on activated charcoal; In tetrahydrofuran; isopropyl alcohol; acetonitrile;
DOI:10.1016/j.tet.2007.05.050