(S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine

Base Information

Chemical Name:(S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine
CAS No.:866783-12-2
Molecular Formula:C12H17NO2
Molecular Weight:207.272
Hs Code.:2922199090
UNII:SH7YT359XL
DSSTox Substance ID:DTXSID30467607
Nikkaji Number:J3.605.798J
Wikidata:Q76421609
Mol file:866783-12-2.mol

Synonyms:866783-12-2;(S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine;SH7YT359XL;1-[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]-N-methylmethanamine;(((7S)-3,4-Dimethoxybicyclo(4.2.0)octa-1(6),2,4-trien-7-yl)methyl)(methyl)amine;(S)-1-(3,4-Dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)-N-methylmethanamine;Bicyclo(4.2.0)octa-1,3,5-triene-7-methanamine, 3,4-dimethoxy-N-methyl-, (7S)-;UNII-SH7YT359XL;SCHEMBL221006;(1S)-4,5-Dimethoxy-1-(methylaminoethyl)benzocyclobutane;DTXSID30467607;SAVVFXUMMFHSJC-SECBINFHSA-N;CS-0055029;(1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane;(1S)-4,5-dimethoxy-1-(methylaminomethyl)benzocyclobutane;(1S)-4,5-dimethyloxy-1-(methylaminomethyl)-benzocyclobutane;4,5-DIMETHOXY-1-(N-METHYLAMINOMETHYL)BENZOCYCLOBUTANE;(1S)-1-(3,4-DIMETHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-YL)-N-METHYLMETHANAMINE;(3,4-Dimethoxy-bicyclo(4.2.0)octa-1 (6),2,4-trien-7-ylmethyl)-methyl-am ine;(3,4-DIMETHOXY-BICYCLO(4.2.0)OCTA-1 (6),2,4-TRIEN-7-YLMETHYL)-METHYLAMINE;[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-N-methylmethanamine;{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}methylamine;1-[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-N-methyl-methanamine

Suppliers and Price of (S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine 95+%
1g
$ 1120.00

Chemenu
(S)-1-(3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine 95%
1g
$ 1056.00

Total 62 raw suppliers

Chemical Property of (S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine

Chemical Property:

PSA：30.49000
LogP:1.95380
Storage Temp.:2-8°C
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:207.125928785
Heavy Atom Count:15
Complexity:210

Purity/Quality:

99% ^*data from raw suppliers

(S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNCC1CC2=CC(=C(C=C12)OC)OC
Isomeric SMILES:CNC[C@H]1CC2=CC(=C(C=C12)OC)OC
Uses (S)-N-((3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylacetamide is a derivative of (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane (D461760, HCl); an intermediate in the synthesis of Ivabradine (I940500, HCl) which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node. Also an antianginal.

Technology Process of (S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine

There total 21 articles about (S)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N-methylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: (1S)-4,5-dimethoxy-1-[(methylamino)methyl]benzocyclobutane N-acetyl-L-glutamic acid

: 866783-12-2
[{(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl}methyl](methyl)amine

Guidance literature:: With sodium hydroxide; In ethanol; dichloromethane; water; at 20 ℃; for 1h; pH=10 - 11;

Reference yield: 96.0%

: (1S)-4,5-dimethoxy-1-[(methylamino)methyl]benzocyclobutane dextro mandelate

: 866783-12-2
[{(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl}methyl](methyl)amine

Guidance literature:: With sodium hydroxide; In dichloromethane; water; at 20 ℃; for 1h; pH=10 - 11;

Reference yield: 93.0%

: 869856-10-0
ethyl {[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}carbamate

: 866783-12-2
[{(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl}methyl](methyl)amine

Guidance literature:: ethyl {[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}carbamate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 1h; Heating / reflux;

With sodium hydroxide; water; In tetrahydrofuran; at 15 ℃;