Chemical Property of Quisinostat
Chemical Property:
- Refractive Index:1.688
- Boiling Point:615.103 °C at 760 mmHg
- Flash Point:325.803 °C
- PSA：95.31000
- Density:1.274 g/cm3
- LogP:2.94030
- Solubility.:insoluble in H2O; insoluble in EtOH; ≥19.2 mg/mL in DMSO
- XLogP3:1.3
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:6
- Exact Mass:394.21172409
- Heavy Atom Count:29
- Complexity:533
- Purity/Quality:
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99%, *data from raw suppliers
N-Hydroxy-2-(4-((((1-methyl-1H-indol-3-yl)methyl)amino)-methyl)piperidin-1-yl)pyrimidine-5-carboxamide 95%+ *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CN1C=C(C2=CC=CC=C21)CNCC3CCN(CC3)C4=NC=C(C=N4)C(=O)NO
- Recent ClinicalTrials:Safety and Efficacy of Quisinostat, a Histone Deacetylase Inhibitor, in Combination With Chemotherapy
- Recent EU Clinical Trials:A Phase 2, Single-arm, Open-label, Multicenter Study of the Histone
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Uses
JNJ-26481585 is an HDAC1, HDAC2, HDAC4, HDAC10, and HDAC11 inhibitor. Potent Histone deacetylase inhibitor.
