(R)-1-Boc-3-piperidineacetic acid methyl ester

Base Information

• Chemical Name: (R)-1-Boc-3-piperidineacetic acid methyl ester
• CAS No.: 865157-02-4
• Molecular Formula: C₁₃H₂₃NO₄
• Molecular Weight: 257.33
• Hs Code.: 2933399090
• Mol file: 865157-02-4.mol

Synonyms:(R)-1-Boc-3-Piperidine acetate methyl ester;(R)-N-Boc-3-Piperidine acetic acid methyl ester;(R)-Tert-butyl 3-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate;

Chemical Property of (R)-1-Boc-3-piperidineacetic acid methyl ester

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 323.121°C at 760 mmHg
• PKA: -1.99±0.40(Predicted)
• Flash Point: 149.219°C
• PSA: 55.84000
• Density: 1.062g/cm³
• LogP: 2.13450
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

(R)-tert-Butyl3-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-1-Boc-3-piperidineacetic acid methyl ester

There total 1 articles about (R)-1-Boc-3-piperidineacetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl-(R)-3-piperidine acetate hydrochloride (865157-03-5,247259-31-0,957471-98-6) + di-tert-butyl dicarbonate (24424-99-5) → (R)-3-methoxycarbonylmethyl-piperidine-1-carboxylic acid tert-butyl ester (865157-02-4)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h;

upstream raw materials:

methyl-(R)-3-piperidine acetate hydrochloride

di-tert-butyl dicarbonate