6,8-Dibromo-4-chloroquinazoline

Base Information

Chemical Name:6,8-Dibromo-4-chloroquinazoline
CAS No.:98436-45-4
Molecular Formula:C₈H₃Br₂ClN₂
Molecular Weight:322.386
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00559801
Wikidata:Q82442649
Mol file:98436-45-4.mol

Synonyms:6,8-Dibromo-4-chloroquinazoline;98436-45-4;6,8-Dibromo-4-chloro-quinazoline;SCHEMBL3796785;DTXSID00559801;AKOS009144089;CS-0257799;EN300-67799;Z277541242

Suppliers and Price of 6,8-Dibromo-4-chloroquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6,8-Dibromo-4-chloroquinazoline 95+%
1g
$ 402.00

Chemenu
6,8-dibromo-4-chloroquinazoline 95%
1g
$ 380.00

American Custom Chemicals Corporation
6,8-DIBROMO-4-CHLORO-QUINAZOLINE 98.00%
5MG
$ 502.81

Alichem
6,8-Dibromo-4-chloroquinazoline
1g
$ 360.80

Total 7 raw suppliers

Chemical Property of 6,8-Dibromo-4-chloroquinazoline

Chemical Property:

PSA：25.78000
LogP:3.80820
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:321.83310
Heavy Atom Count:13
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

6,8-Dibromo-4-chloroquinazoline 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C2=C1C(=NC=N2)Cl)Br)Br

Technology Process of 6,8-Dibromo-4-chloroquinazoline

There total 3 articles about 6,8-Dibromo-4-chloroquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 17518-85-3
6,8-dibromo-3,4-dihydro-4-oxo-quinazoline

: 98436-45-4
6,8‐dibromo‐4‐chloroquinazoline

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-aniline; at 60 - 70 ℃; for 2h; Inert atmosphere;
DOI:10.3109/14756366.2012.755622

Reference yield:

: 609-85-8
2-amino-3,5-dibromobenzoic acid

: 98436-45-4
6,8‐dibromo‐4‐chloroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 180 °C

2: POCl₃; PCl₅

With phosphorus pentachloride; trichlorophosphate;

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 98436-45-4
6,8‐dibromo‐4‐chloroquinazoline

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; bromine / Reflux; Inert atmosphere

2: 6 h / 160 °C / Inert atmosphere

3: trichlorophosphate / N,N-dimethyl-aniline / 2 h / 60 - 70 °C / Inert atmosphere

With bromine; acetic acid; trichlorophosphate; In N,N-dimethyl-aniline;
DOI:10.3109/14756366.2012.755622