(6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol

Base Information

Chemical Name:(6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol
CAS No.:500765-68-4
Molecular Formula:C₁₂H₁₇NO₃
Molecular Weight:223.272
Hs Code.:2933499090
Mol file:500765-68-4.mol

Synonyms:(6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-3-YL)-METHANOL

Suppliers and Price of (6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-3-YL)-METHANOL 95.00%
5MG
$ 498.98

Total 4 raw suppliers

Chemical Property of (6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol

Chemical Property:

PSA：50.72000
LogP:1.03920

Purity/Quality:

98%min ^*data from raw suppliers

(6,7-DIMETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-3-YL)-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol

There total 1 articles about (6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 76824-86-7
6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

: 500765-68-4
(6,7-dimethoxy-1,2,3,4-tetrahydro-3-isoquinolyl)methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 8h; Heating;
DOI:10.1016/j.tet.2006.01.018

Reference yield: 24.0%

: 500765-68-4
(6,7-dimethoxy-1,2,3,4-tetrahydro-3-isoquinolyl)methanol

: 824-72-6
P,P-dichlorophenylphosphine oxide

: C₁₈H₂₀NO₄P

: C₁₈H₂₀NO₄P

Guidance literature:: With triethylamine; In dichloromethane; at 6 - 20 ℃; optical yield given as %de; diastereoselective reaction;
DOI:10.1002/ejoc.200701026

Reference yield:

: 500765-68-4
(6,7-dimethoxy-1,2,3,4-tetrahydro-3-isoquinolyl)methanol

: (2S,4aR)-6,7-Dimethoxy-2-phenyl-4,4a,9,10-tetrahydro-3-oxa-1,9a-diaza-2-phospha-anthracene 2-oxide

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid; NaNO₂ / H₂O / 8 h / 20 °C

2: 1.60 g / LiAlH₄ / tetrahydrofuran / 2 h / 20 °C

3: 40 percent / Et₃N / tetrahydrofuran / 48 h / 20 °C

With lithium aluminium tetrahydride; acetic acid; triethylamine; sodium nitrite; In tetrahydrofuran; water;
DOI:10.1016/j.tet.2006.01.018