O-METHYL-L-TYROSINE HYDROCHLORIDE

Base Information

• Chemical Name: O-METHYL-L-TYROSINE HYDROCHLORIDE
• CAS No.: 67423-44-3
• Molecular Formula: C10H14ClNO3
• Molecular Weight: 231.68
• Hs Code.: 2922509090
• Mol file: 67423-44-3.mol

Synonyms:H-TYR(ME)-OH HCL;H-TYR(ME)-OH HYDROCHLORIDE;P-METHOXY-L-PHENYLALANINE HYDROCHLORIDE;4-Methoxy-L-PhenylalanineHCl;H-p-Methoxy-Phe-OH.HCl(H-Tyr(Me)-OH.HCl;

Chemical Property of O-METHYL-L-TYROSINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 2.01E-06mmHg at 25°C
• Boiling Point: 379.1°C at 760 mmHg
• Flash Point: 183.1°C
• PSA: 72.55000
• LogP: 2.15190
• Storage Temp.: -20°C

Purity/Quality:

98%min ^*data from raw suppliers

H-Phe(4-OMe)-OH.HCl 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of O-METHYL-L-TYROSINE HYDROCHLORIDE

There total 6 articles about O-METHYL-L-TYROSINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-acetylamino-2-(4-methoxybenzyl)malonic acid diethyl ester (53612-87-6) → 2-amino-3-(4-methoxyphenyl)propionic acid hydrochloride (67423-44-3,70601-63-7,99075-81-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; water; Heating;

DOI:10.1016/j.ejmech.2005.01.002

Reference yield:

2-((tert-butoxycarbonyl)amino)-3-(4-methoxyphenyl)-2-methylpropanoic acid → 2-amino-3-(4-methoxyphenyl)propionic acid hydrochloride (67423-44-3,70601-63-7,99075-81-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

ethyl 2-acetylamino-2-cyano-3-(4-methoxyphenyl)propanoate (81961-88-8) → 2-amino-3-(4-methoxyphenyl)propionic acid hydrochloride (67423-44-3,70601-63-7,99075-81-7)

Guidance literature:

With hydrogenchloride; water; for 30h; Reflux;

DOI:10.1016/j.tet.2014.02.012

upstream raw materials:

2-acetylamino-2-(4-methoxybenzyl)malonic acid diethyl ester

ethyl 2-acetylamino-2-cyano-3-(4-methoxyphenyl)propanoate

p-methoxybenzyl chloride

O-methyl-tyrosine methyl ester; hydrochloride

Downstream raw materials:

2-(((benzyloxy)carbonyl)amino)-3-(4-methoxyphenyl)propanoic acid

O-methyl-N-tert-butoxycarbonyl-L-tyrosine

(S)-2-((methoxycarbonyl)amino)-3-(4-methoxyphenyl)propanoic acid

6-(dimethylamino)-9-<3'-<amino>-5'-chloro-3',5'-dideoxy-β-D-ribofuranosyl>purine