Technology Process of 3-iodo-1-phenyl-1H-pyrazole
There total 3 articles about 3-iodo-1-phenyl-1H-pyrazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
iodine;
In
tetrahydrofuran;
for 1h;
Ambient temperature;
- Guidance literature:
-
3-amino-1-phenylpyrazole;
With
hydrogenchloride; sodium nitrite;
In
tetrahydrofuran; water;
for 0.333333h;
Cooling with ice;
With
potassium iodide;
In
tetrahydrofuran; water;
at 20 ℃;
for 1.16667h;
Cooling with ice;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: copper(ll) bromide; caesium carbonate / N,N-dimethyl-formamide / 0.33 h / 190 °C / Microwave irradiation; Sealed tube
2.1: hydrogenchloride; sodium nitrite / tetrahydrofuran; water / 0.33 h / Cooling with ice
2.2: 1.17 h / 20 °C / Cooling with ice
With
hydrogenchloride; caesium carbonate; copper(ll) bromide; sodium nitrite;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;