3-Hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

Base Information

Chemical Name:3-Hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one
CAS No.:17792-11-9
Molecular Formula:C₁₈H₂₁NO₄
Molecular Weight:315.369
Hs Code.:
NSC Number:113784
DSSTox Substance ID:DTXSID60419053
Wikidata:Q82229850
ChEMBL ID:CHEMBL1487479

Synonyms:17792-11-9;3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one;MLS000078642;SMR000037571;NSC113784;Oprea1_204075;Oprea1_268460;CHEMBL1487479;BDBM51488;cid_5381219;DTXSID60419053;HMS2176A17;EiM07-15977;STL303459;AKOS002345960;CCG-349827;NSC-113784;3-hydroxy-4-(morpholinomethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one;3-hydroxy-4-morpholinomethyl-7,8,9,10-tetrahydro-6h-benzo[c]chromen-6-one;3-hydroxy-4-(4-morpholinylmethyl)-7,8,9,10-tetrahydrobenzo[c][1]benzopyran-6-one;3-hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one;3-hydroxy-4-(morpholinomethyl)-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one;4-(morpholin-4-ylmethyl)-3-oxidanyl-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

Suppliers and Price of 3-Hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-Hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

Chemical Property:

Vapor Pressure:4.22E-12mmHg at 25°C
Melting Point:146-147 °C
Boiling Point:536.0±50.0 °C(Predicted)
PKA:8.77±0.20(Predicted)
Density:1.34±0.1 g/cm3(Predicted)
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:315.14705815
Heavy Atom Count:23
Complexity:497

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC2=C(C1)C3=C(C(=C(C=C3)O)CN4CCOCC4)OC2=O

Technology Process of 3-Hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

There total 4 articles about 3-Hydroxy-4-(morpholin-4-ylmethyl)-7,8,9,10-tetrahydrobenzo[c]chromen-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 5625-90-1
4-(morpholinomethyl)morpholine

: 3722-44-9
3-hydroxy-7,8,9,10-tetrahydrobenzo[c]chromen-6-one

: 17792-11-9
3-hydroxy-4-morpholinomethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one

Guidance literature:: In 1,4-dioxane; at 100 ℃;
DOI:10.1023/A:1022674318345

Reference yield:

: 1655-07-8
ethyl 2-oxocyclohexane carboxylate

: 17792-11-9
3-hydroxy-4-morpholinomethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / conc. H₂SO₄ / ethanol / 0 - 20 °C

2: 91 percent / dioxane / 100 °C

With sulfuric acid; In 1,4-dioxane; ethanol; 1: Pechmann condensation / 2: Mannich reaction;
DOI:10.1023/A:1022674318345

Reference yield:

: 108-46-3
recorcinol

: 17792-11-9
3-hydroxy-4-morpholinomethyl-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / conc. H₂SO₄ / ethanol / 0 - 20 °C

2: 91 percent / dioxane / 100 °C

With sulfuric acid; In 1,4-dioxane; ethanol; 1: Pechmann condensation / 2: Mannich reaction;
DOI:10.1023/A:1022674318345