15-Methyl-PGF2alpha

Base Information

• Chemical Name: 15-Methyl-PGF2alpha
• CAS No.: 76498-29-8
• Molecular Formula: C₂₁H₃₆O₅
• Molecular Weight: 368.514
• UNII: V0STI57XNU
• ChEMBL ID: CHEMBL1909299
• Mol file: 76498-29-8.mol

Synonyms:trans-Carboprost;15-Methyl-PGF2alpha;V0STI57XNU;76498-29-8;trans-Carboprost [USP];UNII-V0STI57XNU;(E)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(3S)-3-hydroxy-3-methyloct-1-enyl)cyclopentyl)-5-heptenoic acid;(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid;Prosta-5,13-dien-1-oic acid, 9,11,15-trihydroxy-15-methyl-, (5E,9alpha,11alpha,13E,15S)-;SCHEMBL340643;CHEMBL1909299;DLJKPYFALUEJCK-MRVZPHNRSA-N;CARBOPROSTTROMETHAMINE(25MG);AKOS015892797;TRANS-CARBOPROST [USP IMPURITY];A831920

Chemical Property of 15-Methyl-PGF2alpha

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 12
• Exact Mass: 368.25627424
• Heavy Atom Count: 26
• Complexity: 473

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC(C)(C=CC1C(CC(C1CC=CCCCC(=O)O)O)O)O
• Isomeric SMILES: CCCCC[C@@](C)(/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C/CCCC(=O)O)O)O)O

Technology Process of 15-Methyl-PGF2alpha

There total 2 articles about 15-Methyl-PGF2alpha which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (Z)-7-[(1R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hydroxy-3-methyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid (35700-23-3,35700-24-4,35700-25-5,35864-81-4,41691-84-3,59286-19-0,62446-63-3,62776-95-8,68906-67-2,68906-68-3,76498-29-8,80124-57-8,90695-58-2,90695-59-3,100019-29-2,113626-85-0)

Guidance literature:

15-Oxo-1,9,11-tris-OSi(Me)3-PGF(2α), 1.) MeMgBr, 2.) W.;

Reference yield:

→ (Z)-7-[(1R,3R)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-3-methyl-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid (35700-23-3,35700-24-4,35700-25-5,35864-81-4,41691-84-3,59286-19-0,62446-63-3,62776-95-8,68906-67-2,68906-68-3,76498-29-8,80124-57-8,90695-58-2,90695-59-3,100019-29-2,113626-85-0)

Guidance literature:

TMS-Derivat v. 15-Oxo-PGF(2β) u. CH3MgBr;