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Technology Process of N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

Base Information
  • Chemical Name:N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
  • CAS No.:875337-44-3
  • Molecular Formula:C26H20FN5O2S2
  • Molecular Weight:517.60
  • Hs Code.:
  • Mol file:875337-44-3.mol
N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide

Synonyms:MGCD-265

Suppliers and Price of N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • MGCD-265
  • 50mg
  • $ 1025.00
  • TRC
  • MGCD-265
  • 10mg
  • $ 310.00
  • Medical Isotopes, Inc.
  • MGCD-265
  • 5 mg
  • $ 650.00
  • Medical Isotopes, Inc.
  • MGCD-265
  • 50 mg
  • $ 1475.00
  • Matrix Scientific
  • N-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbAmothioyl)-2-phenylacetamide 95%
  • 50mg
  • $ 1203.00
  • Matrix Scientific
  • N-(3-Fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbAmothioyl)-2-phenylacetamide 95%
  • 1g
  • $ 3691.00
  • DC Chemicals
  • MGCD-265 >98%
  • 1 g
  • $ 2000.00
  • DC Chemicals
  • MGCD-265 >98%
  • 250 mg
  • $ 1000.00
  • DC Chemicals
  • MGCD-265 >98%
  • 100 mg
  • $ 500.00
  • Crysdot
  • MGCD-265analog 98+%
  • 50mg
  • $ 694.00
Total 73 raw suppliers
Chemical Property of N-(3-fluoro-4-(2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Chemical Property:
  • Appearance/Colour:White to off-white solid 
  • Refractive Index:1.707 
  • Boiling Point:195.7 °C at 760 mmHg 
  • PKA:10.07±0.70(Predicted) 
  • Flash Point:72.1 °C 
  • PSA：151.93000 
  • Density:1.771g/cm3 
  • LogP:6.74470 
  • Solubility.:≥25.9 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O 
Purity/Quality:

99%, *data from raw suppliers

MGCD-265 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses MGCD-265 is a multi-targeted kinase inhibitor, which targets the c-MET, VEGFR1, VEGFR2, VEGFR3, Tie-2 and Ron receptor tyrosine kinases. MGCD-265 is a novel dual c-Met/ VEGFR2 receptor tyrosine kinase inhibitor possessing favorable pharmacokinetic profiles and showed high efficacy in vivo in several human tumor xenograft models in mice . MGCD-265 is a novel dual c-Met/ VEGFR2 receptor tyrosine kinase inhibitor possessing favorable pharmacokinetic profiles and showed high efficacy in vivo in several human tumor xenograft models in mice.
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