Quarfloxin

Base Information

Chemical Name:Quarfloxin
CAS No.:865311-47-3
Molecular Formula:C₃₅H₃₃FN₆O₃
Molecular Weight:604.684
Hs Code.:
UNII:8M31J5031Q
ChEMBL ID:CHEMBL3989407
Metabolomics Workbench ID:149876
NCI Thesaurus Code:C71726
Wikidata:Q27270731
Mol file:865311-47-3.mol

Synonyms:CX 3543;CX-3543;CX3543

Suppliers and Price of Quarfloxin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Quarfloxin(CX-3543) >98%
100 mg
$ 1350.00

DC Chemicals
Quarfloxin(CX-3543) >98%
10 mg
$ 450.00

ChemScene
Quarfloxin 99.95%
5mg
$ 350.00

ChemScene
Quarfloxin 99.95%
1mg
$ 150.00

ChemScene
Quarfloxin 99.95%
10mg
$ 600.00

ChemScene
Quarfloxin 99.95%
50mg
$ 1000.00

ChemScene
Quarfloxin 99.95%
100mg
$ 1800.00

Biorbyt Ltd
Quarfloxin (CX-3543) >98%
100 mg
$ 2839.00

Biorbyt Ltd
Quarfloxin (CX-3543) >98%
25 mg
$ 1504.50

Biorbyt Ltd
Quarfloxin (CX-3543) >98%
10 mg
$ 912.90

Total 35 raw suppliers

Chemical Property of Quarfloxin

Chemical Property:

Boiling Point:845.3±65.0 °C(Predicted)
PKA:11.46±0.20(Predicted)
PSA：99.47000
Density:1.44
LogP:6.06690
XLogP3:5.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:604.25981710
Heavy Atom Count:45
Complexity:1150

Purity/Quality:

99%, ^*data from raw suppliers

Quarfloxin(CX-3543) >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCC1CCNC(=O)C2=CN3C4=CC5=CC=CC=C5C=C4OC6=C3C(=CC(=C6N7CCC(C7)C8=NC=CN=C8)F)C2=O
Isomeric SMILES:CN1CCC[C@H]1CCNC(=O)C2=CN3C4=CC5=CC=CC=C5C=C4OC6=C3C(=CC(=C6N7CCC(C7)C8=NC=CN=C8)F)C2=O
Recent ClinicalTrials:Quarfloxin in Patients With Low to Intermediate Grade Neuroendocrine Carcinoma

Technology Process of Quarfloxin

There total 3 articles about Quarfloxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

: 422545-96-8
{2-[(2R)-1-methylpyrrolidin-2-yl]ethyl}amine

: 876060-50-3
C₃₀H₂₃FN₄O₄

: 876059-62-0,865311-47-3
5-Fluoro-N-[2-[1-methylpyrrolidin-2(R)-yl]ethyl]-3-oxo-6-[3-(2-pyrazinyl)pyrrolidin-1-yl]-3H-benzo[b]pyrido[3,2,1-kl]phenoxazine-2-carboxamide

Guidance literature:: With aluminum (III) chloride; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.tetlet.2010.12.108

Reference yield:

: 422545-95-7,422545-96-8
(S)-2-(1-methylpyrrolidin-2-yl)ethan-1-amine

: 876060-50-3
C₃₀H₂₃FN₄O₄

: 865311-47-3
quarfloxin

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 422545-95-7,422545-96-8
(S)-2-(1-methylpyrrolidin-2-yl)ethan-1-amine

: 876060-51-4
C₂₈H₁₉FN₄O₄

: 865311-47-3
quarfloxacin

Guidance literature:: C₂₈H₁₉FN₄O₄; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 1h;

(S)-2-(1-methylpyrrolidin-2-yl)ethan-1-amine; In 1-methyl-pyrrolidin-2-one; for 0.5h;