C₁₆H₂₀O

Base Information

• Chemical Name: C₁₆H₂₀O
• CAS No.: 1432499-25-6
• Molecular Formula: C₁₆H₂₀O
• Molecular Weight: 228.334
• Mol file: 1432499-25-6.mol

Synonyms:

Chemical Property of C₁₆H₂₀O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₀O

There total 3 articles about C₁₆H₂₀O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H16O (1432499-24-5) + propargyl bromide (106-96-7) → C16H20O (1432499-25-6)

Guidance literature:

With ammonium chloride; zinc; In tetrahydrofuran; water; toluene; at 0 - 20 ℃; for 4h; Inert atmosphere;

DOI:10.1021/ja4025963

Reference yield:

C15H21NO (1432499-23-4) → C16H20O (1432499-25-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diisobutylaluminium hydride / toluene / 4 h / -78 - 0 °C / Inert atmosphere

2: zinc; ammonium chloride / toluene; water; tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

With diisobutylaluminium hydride; ammonium chloride; zinc; In tetrahydrofuran; water; toluene;

DOI:10.1021/ja4025963

Reference yield:

N,N-dimethyl-2-(2-methylphenyl)ethanamide (3917-57-5) → C16H20O (1432499-25-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 20 h / 20 °C / Inert atmosphere

2.1: diisobutylaluminium hydride / toluene / 4 h / -78 - 0 °C / Inert atmosphere

3.1: zinc; ammonium chloride / toluene; water; tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

With diisobutylaluminium hydride; ammonium chloride; zinc; lithium diisopropyl amide; In tetrahydrofuran; water; toluene;

DOI:10.1021/ja4025963

upstream raw materials:

C₁₃H₁₆O

propargyl bromide

N,N-dimethyl-2-(2-methylphenyl)ethanamide

C₁₅H₂₁NO

Downstream raw materials:

C₁₆H₁₈O