4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine

Base Information

Chemical Name:4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine
CAS No.:870221-22-0
Molecular Formula:C10H9ClN4
Molecular Weight:220.661
Hs Code.:2933990090
DSSTox Substance ID:DTXSID40582976
Wikidata:Q82474487
Mol file:870221-22-0.mol

Synonyms:4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine;870221-22-0;4-(2-chloropyridin-3-yl)-N-methylpyrimidin-2-amine;SCHEMBL580408;DTXSID40582976;SPRHXGPRWSLRNY-UHFFFAOYSA-N;VJB22122;MFCD12922716;AKOS005073428;KD-0755;CS-0456732;E72631;J-513294;[4-(2-chloro-pyridin-3-yl)-pyrimidin-2-yl]-methyl-amine

Suppliers and Price of 4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine >95%
500mg
$ 485.00

Matrix Scientific
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine >95%
1g
$ 655.00

Matrix Scientific
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine >95%
5g
$ 2485.00

Crysdot
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine 95+%
1g
$ 683.00

Chemenu
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine 95%
1g
$ 645.00

American Custom Chemicals Corporation
4-(2-CHLORO-3-PYRIDINYL)-N-METHYL-2-PYRIMIDINAMINE 95.00%
1G
$ 728.70

American Custom Chemicals Corporation
4-(2-CHLORO-3-PYRIDINYL)-N-METHYL-2-PYRIMIDINAMINE 95.00%
5MG
$ 495.75

Alichem
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine
1g
$ 550.44

AK Scientific
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine
5g
$ 3404.00

AK Scientific
4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine
500mg
$ 704.00

Total 8 raw suppliers

Chemical Property of 4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine

Chemical Property:

Vapor Pressure:1.21E-06mmHg at 25°C
Melting Point:187～189℃
Boiling Point:401.1°C at 760 mmHg
Flash Point:196.4°C
PSA：50.70000
Density:1.33g/cm³
LogP:2.30670
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:220.0515740
Heavy Atom Count:15
Complexity:202

Purity/Quality:

98%min ^*data from raw suppliers

4-(2-Chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=NC=CC(=N1)C2=C(N=CC=C2)Cl

Technology Process of 4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine

There total 3 articles about 4-(2-chloro-3-pyridinyl)-N-methyl-2-pyrimidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 166196-84-5
1-(2-chloropyridin-3-yl)-3-dimethylaminopropenone

: 22661-87-6,21770-81-0
1-methylguanidine hydrochloride

: 870221-22-0
4-(2-chloropyridin-3-yl)-N-methylpyrimidin-2-amine

Guidance literature:: 1-methylguanidine hydrochloride; With sodium methylate; In methanol; for 0.5h;

1-(2-chloropyridin-3-yl)-3-dimethylaminopropenone; In methanol; at 50 ℃; for 23h;
DOI:10.1021/jm061107l

Reference yield:

: 1-(2-chloro-pyridin-3-yl)-3-dimethylamino-propenone

: 22661-87-6,21770-81-0
1-methylguanidine hydrochloride

: 870221-22-0
4-(2-chloropyridin-3-yl)-N-methylpyrimidin-2-amine

Guidance literature:: 1-methylguanidine hydrochloride; With sodium methylate; In methanol; at 20 ℃; for 0.5h;

1-(2-chloro-pyridin-3-yl)-3-dimethylamino-propenone; In methanol; at 50 ℃; for 23h;

Reference yield:

: 55676-21-6
3-acetyl-2-chloropyridine

: 870221-22-0
4-(2-chloropyridin-3-yl)-N-methylpyrimidin-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: 56 percent / 1.5 h / 85 °C

2.1: NaOMe / methanol / 0.5 h

2.2: 90 percent / methanol / 23 h / 50 °C

With sodium methylate; In methanol;
DOI:10.1021/jm061107l