Technology Process of 5-bromo-2,2'-bis(hydroxymethyl)diphenylmethane
There total 8 articles about 5-bromo-2,2'-bis(hydroxymethyl)diphenylmethane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dimethylsulfide borane complex;
In
dichloromethane;
at 20 ℃;
for 24h;
DOI:10.1055/s-2002-23541
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 82 percent / NaOAc / 3 h / 230 - 240 °C
2.1: 85 percent / aq. HI; red phosphorus; H3PO2 / 24 h / Heating
3.1: 64 percent / polyphosphoric acid / 5 h / 175 °C
4.1: PCl5; POCl3 / 3 h / 100 °C
4.2: toluene / 20 °C
4.3: 89 percent / aq. MeOH / 2 h / 20 °C
5.1: 89 percent / Al(i-PrO)3 / 3 h / 275 °C
6.1: O3 / CH2Cl2 / 2 h / -78 °C
7.1: 0.42 g / BH3*S(CH3)2 / CH2Cl2 / 24 h / 20 °C
With
phosphorus; PPA; dimethylsulfide borane complex; phosphorus pentachloride; hydrogen iodide; sodium acetate; hypophosphorous acid; aluminum isopropoxide; ozone; trichlorophosphate;
In
dichloromethane;
DOI:10.1055/s-2002-23541
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 85 percent / aq. HI; red phosphorus; H3PO2 / 24 h / Heating
2.1: 64 percent / polyphosphoric acid / 5 h / 175 °C
3.1: PCl5; POCl3 / 3 h / 100 °C
3.2: toluene / 20 °C
3.3: 89 percent / aq. MeOH / 2 h / 20 °C
4.1: 89 percent / Al(i-PrO)3 / 3 h / 275 °C
5.1: O3 / CH2Cl2 / 2 h / -78 °C
6.1: 0.42 g / BH3*S(CH3)2 / CH2Cl2 / 24 h / 20 °C
With
phosphorus; PPA; dimethylsulfide borane complex; phosphorus pentachloride; hydrogen iodide; hypophosphorous acid; aluminum isopropoxide; ozone; trichlorophosphate;
In
dichloromethane;
DOI:10.1055/s-2002-23541
