16β-phenyltestosterone

Base Information

• Chemical Name: 16β-phenyltestosterone
• CAS No.: 51477-63-5
• Molecular Formula: C₂₅H₃₂O₂
• Molecular Weight: 364.528
• Mol file: 51477-63-5.mol

Synonyms:

Chemical Property of 16β-phenyltestosterone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16β-phenyltestosterone

There total 2 articles about 16β-phenyltestosterone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3S,8R,9S,10R,13S,14S,16R)-3-Hydroxy-10,13-dimethyl-16-phenyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-17-one → 16β-phenyltestosterone (51477-63-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Al(OiPr)3, cyclohexanone / benzene

2: (i) HC(OEt)3, TsOH, dioxane, (ii) NaBH₄, MeOH, (iii) aq. HCl

With cyclohexanone; aluminum isopropoxide; In benzene;

DOI:10.1248/cpb.26.1718

Reference yield:

16β-Phenyl-androst-4-en-3,17-dion (67850-49-1) → 16β-phenyltestosterone (51477-63-5)

Guidance literature:

Multistep reaction; (i) HC(OEt)3, TsOH, dioxane, (ii) NaBH₄, MeOH, (iii) aq. HCl;

DOI:10.1248/cpb.26.1718

upstream raw materials:

16β-Phenyl-androst-4-en-3,17-dion