2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Base Information

• Chemical Name: 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
• CAS No.: 2914-78-5
• Molecular Formula: C₁₆H₂₅NO₂*ClH
• Molecular Weight: 299.841
• European Community (EC) Number: 683-089-4
• ChEMBL ID: CHEMBL1237065
• Mol file: 2914-78-5.mol

Synonyms:Adolonta;Amadol;Biodalgic;Biokanol;Contramal;Jutadol;K 315;K-315;K315;MTW Tramadol;MTW-Tramadol;MTWTramadol;Nobligan;Prontofort;Ranitidin 1A Pharma;Takadol;Theradol;Tiral;Topalgic;Tradol;Tradol Puren;Tradol-Puren;TradolPuren;Tradonal;Tralgiol;Trama 1A Pharma;Trama AbZ;Trama Dorsch;Trama KD;Trama-Dorsch;Tramabeta;Tramadin;Tramadoc;Tramadol;Tramadol 1A;Tramadol acis;Tramadol AL;Tramadol Asta Medica;Tramadol Basics;Tramadol Bayvit;Tramadol Bexal;Tramadol Cinfa;Tramadol Dolgit;Tramadol Edigen;Tramadol Hameln;Tramadol Heumann;Tramadol Hydrochloride;Tramadol Kern;Tramadol Lichtenstein;Tramadol Lindo;Tramadol Mabo;Tramadol Normon;Tramadol PB;Tramadol Ratiopharm;Tramadol Stada;Tramadol-Dolgit;Tramadol-Hameln;Tramadol-ratiopharm;TramadolDolgit;TramadolHameln;Tramadolor;Tramadolratiopharm;TramaDorsch;Tramadura;Tramagetic;Tramagit;Tramake;Tramal;Tramex;Tramundin;Trasedal;Ultram;Xymel 50;Zamudol;Zumalgic;Zydol;Zytram

Chemical Property of 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

Chemical Property:

• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 299.1652068
• Heavy Atom Count: 20
• Complexity: 282

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC1CCCCC1(C2=CC(=CC=C2)OC)O.Cl
• Recent EU Clinical Trials: Tramadol iv. : influence of dose and dose intervals on therapeutic accuracy and side effects when used for postoperative pain relief in ambulatory surgery

Technology Process of 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

There total 1 articles about 2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(±)-(1R,2S)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol (2914-77-4,27203-92-5,73806-46-9,123134-25-8,123154-38-1,152538-36-8,181289-58-7,181289-59-8) + cis-tramadol (27203-92-5,2914-77-4,73806-46-9,123134-25-8,123154-38-1,36282-47-0,152538-36-8,181289-58-7,181289-59-8) → DL-Tramadolhydrochlorid (2914-78-5,36282-47-0,36406-85-6,36474-71-2,53611-16-8,73806-49-2,148229-78-1,148229-79-2,22204-88-2) + tramadol hydrochloride (36282-47-0,22204-88-2)

Guidance literature:

With hydrogenchloride; In diethyl ether; Product distribution / selectivity;

upstream raw materials:

(±)-(1R,2S)-2-(dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol

cis-tramadol