diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate

Base Information

Chemical Name:diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate
CAS No.:1025062-70-7
Molecular Formula:C₃₆H₄₅N₇O₈
Molecular Weight:703.795
Hs Code.:

diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate

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Chemical Property of diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate

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Technology Process of diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate

There total 1 articles about diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1024676-74-1
1-(9-((2S,3aS,4R,6R,6aS)-6-(aminomethyl)-2-styryl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-yl)-3-ethylurea

: 13949-93-4
(+/-)-ethyl trans-2-formyl-1-cyclopropanecarboxylate

: 1024676-83-2
ethyl 2-((((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylamino)methyl)cyclopropanecarboxylate

: 1025062-70-7
diethyl 2,2'-(((2S,3aS,4R,6R,6aS)-6-(6-(3-ethylureido)-9H-purin-9-yl)-2-styryltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methylazanediyl)bis(methylene)dicyclopropanecarboxylate

Guidance literature:: 1-(9-((2S,3aS,4R,6R,6aS)-6-(aminomethyl)-2-styryl-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-yl)-3-ethylurea; (+/-)-ethyl trans-2-formyl-1-cyclopropanecarboxylate; With acetic acid; In 1,2-dichloro-ethane; for 0.5h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; Further stages.;
DOI:10.1016/j.bmcl.2008.01.038