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Ascomycin, Streptomyces hygroscopicus

Base Information
  • Chemical Name:Ascomycin, Streptomyces hygroscopicus
  • CAS No.:11011-38-4
  • Molecular Formula:C43H69NO12
  • Molecular Weight:792.02
  • Hs Code.:
  • European Community (EC) Number:435-850-5,658-052-0
  • Wikipedia:Ascomycin
  • ChEMBL ID:CHEMBL4303489
Ascomycin, Streptomyces hygroscopicus

Synonyms:ascomycin;changchuanmycin;FK 520;FK-520;FR 900520;FR-900520;immunomycin;tacrolimus related compound A

Suppliers and Price of Ascomycin, Streptomyces hygroscopicus
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • Ascomycin
  • 1mg
  • $ 273.00
  • Usbiological
  • Ascomycin
  • 25mg
  • $ 196.00
  • Sigma-Aldrich
  • Ascomycin, Streptomyces hygroscopicus - CAS 11011-38-4 - Calbiochem An ethyl analog of FK506 with similar immunosuppressant properties.
  • 1mg
  • $ 173.90
  • Biorbyt Ltd
  • Ascomycin (Immunomycin,FK-520) >99%
  • 1 g
  • $ 1208.70
  • Biorbyt Ltd
  • Ascomycin (Immunomycin,FK-520) >99%
  • 250 mg
  • $ 615.40
  • Biorbyt Ltd
  • Ascomycin (Immunomycin,FK-520) >99%
  • 100 mg
  • $ 414.80
  • Biorbyt Ltd
  • Ascomycin >99% pure
  • 25 mg
  • $ 300.90
  • Biorbyt Ltd
  • Ascomycin >98%
  • 25 mg
  • $ 280.50
  • Biorbyt Ltd
  • Ascomycin >98%
  • 5 mg
  • $ 127.50
  • Arctom
  • Ascomycin
  • 10mg
  • $ 54.55
Total 78 raw suppliers
Chemical Property of Ascomycin, Streptomyces hygroscopicus
Chemical Property:
  • Appearance/Colour:White Powder 
  • Melting Point:153-157℃ 
  • Refractive Index:1.543 
  • Boiling Point:868.3 °C at 760 mmHg 
  • Flash Point:478.9 °C 
  • PSA:178.36000 
  • Density:1.19 g/cm3 
  • LogP:4.41080 
  • Storage Temp.:-20°C 
  • Solubility.:Soluble in DMSO (up to 50 mg/ml), or in Ethanol (up to 50 mg/ml with warming). 
  • XLogP3:2.5
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:12
  • Rotatable Bond Count:6
  • Exact Mass:791.48197664
  • Heavy Atom Count:56
  • Complexity:1430
Purity/Quality:

99%, *data from raw suppliers

Ascomycin *data from reagent suppliers

Safty Information:
  • Pictogram(s): R20/21/22:; 
  • Hazard Codes: Xn:Harmful;
     
  • Statements: R20/21/22:; 
  • Safety Statements: S36/37:; 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CCC1C=C(CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC)C)C
  • Isomeric SMILES:CCC1/C=C(/CC(CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC1=O)O)C)/C(=C/C4CCC(C(C4)OC)O)/C)O)C)OC)OC)C)\C
  • Description Ascomycin (11011-38-4) is an analog of FK-506 (Cat.# 10-1103). Potent immunosuppressant1. Binds to FKBP122 and inhibits calcineurin and NFAT. Ascomycin displays anti-inflammatory effects in skin diseases3. Cell permeable and active in vivo.
  • Uses A potent immunosuppressive agent and could be used as a potential therapeutic agent for autoimmune diseases.
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