4-MeO-PCP

Base Information

• Chemical Name: 4-MeO-PCP
• CAS No.: 91164-58-8
• Molecular Formula: C18H27NO
• Molecular Weight: 309.879
• Mol file: 91164-58-8.mol

Synonyms:4-Methoxyphencyclidine;

Chemical Property of 4-MeO-PCP

Chemical Property:

• Boiling Point: 381.307 °C at 760 mmHg
• Flash Point: 112.362 °C
• PSA: 12.47000
• Density: 1.035 g/cm³
• LogP: 5.08040
• Storage Temp.: ?20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-methoxy PCP (hydrochloride) ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 16-36/37-45

MSDS Files:

SDS file from LookChem

Useful:

• Description: 3-methoxy PCP is an analog of PCP which binds the NMDA receptor (Ki = 20 nM) and serotonin transporter (Ki = 216 nM) with greater affinity than does PCP (Ki = 59 and 2,234 nM, respectively). The toxicological properties of this compound have not been reported. This product is intended for forensic and research purposes.
• Uses: 3-Methoxy e but differs in terms binding affinity. 3-Methoxy

Technology Process of 4-MeO-PCP

There total 1 articles about 4-MeO-PCP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

1,5-dibromo-pentane (111-24-0) + 1-(3-methoxyphenyl)cyclohexan-1-amine (125802-07-5) → N-[1-(3-methoxyphenyl)cyclohexyl]piperidine (91164-58-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 48h;

DOI:10.1002/(SICI)1099-1344(1998090)41:9<843::AID-JLCR136>3.0.CO;2-H

Reference yield: 93.0%

N-[1-(3-methoxyphenyl)cyclohexyl]piperidine (91164-58-8) → N-[1-(3-hydroxyphenyl)cyclohexyl]piperidine (79787-43-2)

Guidance literature:

With hydrogen bromide; acetic acid; at 120 ℃; for 3h;

DOI:10.1002/(SICI)1099-1344(1998090)41:9<843::AID-JLCR136>3.0.CO;2-H

upstream raw materials:

1,5-dibromo-pentane

1-(3-methoxyphenyl)cyclohexan-1-amine

Downstream raw materials:

N-[1-(3-hydroxyphenyl)cyclohexyl]piperidine

Refernces