3-Bromo-5-methoxyanthranilic acid

Base Information

Chemical Name:3-Bromo-5-methoxyanthranilic acid
CAS No.:887577-86-8
Molecular Formula:C₈H₈BrNO₃
Molecular Weight:246.06
Hs Code.:2922509090
Mol file:887577-86-8.mol

Synonyms:3-BROMO-5-METHOXYANTHRANILIC ACID;

Suppliers and Price of 3-Bromo-5-methoxyanthranilic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Amino-3-bromo-5-methoxybenzoicacid 95+%
1g
$ 339.00

American Custom Chemicals Corporation
3-BROMO-5-METHOXYANTHRANILIC ACID 95.00%
5MG
$ 499.18

Alichem
2-Amino-3-bromo-5-methoxybenzoicacid
1g
$ 444.60

Total 7 raw suppliers

Chemical Property of 3-Bromo-5-methoxyanthranilic acid

Chemical Property:

PSA：72.55000
LogP:2.31930

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-3-bromo-5-methoxybenzoicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Bromo-5-methoxyanthranilic acid

There total 1 articles about 3-Bromo-5-methoxyanthranilic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6705-03-9
2-Amino-5-methoxybenzoic acid

: 887577-86-8
2-amino-3-bromo-5-methoxybenzoic acid

Guidance literature:: With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 20 ℃; for 14h;

Reference yield:

: 887577-86-8
2-amino-3-bromo-5-methoxybenzoic acid

: (E)-6-((4-amino-8-(4-(2-cyanovinyl)-2,6-dimethylphenyl)-6-methoxyquinazolin-2-yl)amino)nicotinonitrile trifluoroacetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 3 h / 200 °C

2.1: N,N-dimethyl-formamide; trichlorophosphate / 14 h / 120 °C

3.1: ammonia / ethanol / 14 h / 20 °C

4.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium phosphate monohydrate / N,N-dimethyl-formamide; water / 30 h / 80 °C / Inert atmosphere

5.1: palladium diacetate; N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1-methyl-pyrrolidin-2-one / 2 h / 100 °C / Inert atmosphere

5.2: reverse phase flash chromatography (C-18 RediSep prepacked column)

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium phosphate monohydrate; ammonia; palladium diacetate; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; trichlorophosphate; In 1-methyl-pyrrolidin-2-one; ethanol; water; N,N-dimethyl-formamide; 4.1: |Suzuki Coupling;

Reference yield:

: 887577-86-8
2-amino-3-bromo-5-methoxybenzoic acid

: (E)-3-(4-(4-amino-2-chloro-6-methoxyquinazolin-8-yl)-3,5-dimethylphenyl)acrylonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: 3 h / 200 °C

2: N,N-dimethyl-formamide; trichlorophosphate / 14 h / 120 °C

3: ammonia / ethanol / 14 h / 20 °C

4: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium phosphate monohydrate / N,N-dimethyl-formamide; water / 30 h / 80 °C / Inert atmosphere

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium phosphate monohydrate; ammonia; N,N-dimethyl-formamide; trichlorophosphate; In ethanol; water; N,N-dimethyl-formamide; 4: |Suzuki Coupling;