2-(4-Amino-2-fluorophenyl)acetic acid

Base Information

Chemical Name:2-(4-Amino-2-fluorophenyl)acetic acid
CAS No.:914224-31-0
Molecular Formula:C8H8FNO2
Molecular Weight:169.155
Hs Code.:2926907090
DSSTox Substance ID:DTXSID20596334
Wikidata:Q82491564
Mol file:914224-31-0.mol

Synonyms:914224-31-0;2-(4-Amino-2-fluorophenyl)acetic acid;4-Amino-2-fluorophenylacetic acid;(4-AMINO-2-FLUOROPHENYL)ACETIC ACID;2-(4-Amino-2-fluorophenyl) acetic acid;SCHEMBL2298577;DTXSID20596334;2-fluoro-4-aminophenylacetic acid;OENIGBRUGRNUDR-UHFFFAOYSA-N;MFCD09032899;AKOS006331308;2-(4-amino-2-fluoro-phenyl)acetic acid;AS-63570;CS-0147825;EN300-191249;Z1198183551;1-(1-BENZOFURAN-2-YL)-1-PHENYLMETHANAMINEHYDROCHLORIDE

Suppliers and Price of 2-(4-Amino-2-fluorophenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Amino-2-fluorophenyl)aceticacid
500mg
$ 675.00

Crysdot
2-(4-Amino-2-fluorophenyl)aceticacid 95+%
1g
$ 313.00

American Custom Chemicals Corporation
2-(4-AMINO-2-FLUOROPHENYL) ACETIC ACID 95.00%
5G
$ 1734.23

American Custom Chemicals Corporation
2-(4-AMINO-2-FLUOROPHENYL) ACETIC ACID 95.00%
1G
$ 1067.22

Ambeed
2-(4-Amino-2-fluorophenyl)aceticacid 98%
1g
$ 385.00

Ambeed
2-(4-Amino-2-fluorophenyl)aceticacid 98%
250mg
$ 169.00

Ambeed
2-(4-Amino-2-fluorophenyl)aceticacid 98%
100mg
$ 87.00

Alichem
4-Amino-2-fluorophenylaceticacid
1g
$ 410.80

AHH
2-(4-amino-2-fluorophenyl)aceticacid 97%
5g
$ 690.00

Total 13 raw suppliers

Chemical Property of 2-(4-Amino-2-fluorophenyl)acetic acid

Chemical Property:

PSA：63.32000
LogP:1.61620
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:169.05390666
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

(4-Amino-2-fluorophenyl)aceticacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1N)F)CC(=O)O

Technology Process of 2-(4-Amino-2-fluorophenyl)acetic acid

There total 3 articles about 2-(4-Amino-2-fluorophenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 315228-19-4
2-(2-fluoro-4-nitrophenyl)acetic acid

: 914224-31-0
2-(4-amino-2-fluorophenyl)acetic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethyl acetate; for 5h;

Reference yield:

: 369-34-6
3,4-difluoronitrobenzene

: 914224-31-0
2-(4-amino-2-fluorophenyl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1.5 h / 20 °C / Inert atmosphere

1.2: 0 - 20 °C

2.1: acetic acid; sulfuric acid / water / 100 °C

3.1: palladium on activated charcoal; hydrogen / ethanol

With sulfuric acid; palladium on activated charcoal; hydrogen; sodium hydride; acetic acid; In ethanol; water; N,N-dimethyl-formamide;

Reference yield:

: 318471-58-8
1,3-diethyl 2-(2-fluoro-4-nitrophenyl)propanedioate

: 914224-31-0
2-(4-amino-2-fluorophenyl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; sulfuric acid / water / 100 °C

2: palladium on activated charcoal; hydrogen / ethanol

With sulfuric acid; palladium on activated charcoal; hydrogen; acetic acid; In ethanol; water;