tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate

Base Information

Chemical Name:tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate
CAS No.:1055923-68-6
Molecular Formula:C₄₀H₄₉N₅O₅S
Molecular Weight:711.926
Hs Code.:

tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate

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Chemical Property of tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate

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Technology Process of tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate

There total 1 articles about tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: endo 2-methyl-1-{8-[2-(4-phenylpiperidin-4-yl)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}-1H-benzimidazole dihydrochloride

: 716359-59-0
2-{[(tert-butoxycarbonyl)amino]sulfonyl}benzoic acid

: 1055923-68-6
tert-butyl {2-[(4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyipiperidin-1-yl)carbonyl]phenyl}suifonylcarbamate

Guidance literature:: endo 2-methyl-1-{8-[2-(4-phenylpiperidin-4-yl)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}-1H-benzimidazole dihydrochloride; 2-{[(tert-butoxycarbonyl)amino]sulfonyl}benzoic acid; With N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20 ℃;

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 2h;