Acetic acid, 2-[(2-aminocyclohexyl)oxy]-

Base Information

Chemical Name:Acetic acid, 2-[(2-aminocyclohexyl)oxy]-
CAS No.:127958-79-6
Molecular Formula:C₈H₁₅NO₃
Molecular Weight:173.212
Hs Code.:
DSSTox Substance ID:DTXSID001274123

Synonyms:Acetic acid, 2-[(2-aminocyclohexyl)oxy]-;SCHEMBL6500153;DTXSID001274123;AKOS006315127;127958-79-6

Suppliers and Price of Acetic acid, 2-[(2-aminocyclohexyl)oxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Acetic acid, 2-[(2-aminocyclohexyl)oxy]-

Chemical Property:

XLogP3:-2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:173.10519334
Heavy Atom Count:12
Complexity:160

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(C(C1)N)OCC(=O)O

Technology Process of Acetic acid, 2-[(2-aminocyclohexyl)oxy]-

There total 2 articles about Acetic acid, 2-[(2-aminocyclohexyl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: trans-2-(2'-azidocyclohexyloxy)acetic acid

: 127958-79-6,144409-22-3,774508-34-8,780008-21-1
rac-trans-2-(2'-Aminocyclohexyloxy)acetic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 1h; Ambient temperature;
DOI:10.1016/S0040-4020(01)90182-6

Reference yield:

: 127958-79-6,774508-34-8,780008-21-1
3-(2-aminocyclohexyl)-3-oxapropionic acid

Guidance literature:

Reference yield:

: 127958-79-6,144409-22-3,774508-34-8,780008-21-1
rac-trans-2-(2'-Aminocyclohexyloxy)acetic acid

: 141949-61-3,142034-87-5,142034-88-6
(1'S,2'S)-N-<2-(2'-Acetylaminocyclohexyloxy)acetyl>-L-alanyl-D-glutamic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1) 1N NaOH / 1) 5 deg C, 2) 5 deg C, 30 min

2: 0.32 g / diphenylphosphoryl azide, NEt₃ / dimethylformamide / a) 0-2 deg C, 1 h, b) r.t., 60 h

3: 98 percent / H₂ / 10percent Pd/C / methanol / 1 h / Ambient temperature

With sodium hydroxide; diphenylphosphoranyl azide; hydrogen; triethylamine; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)90182-6