1,6-Anhydro-2-azido-2-deoxy-4-o-[(1,1-dimethylethyl)diphenylsilyl]-beta-D-glucopyranose3-acetate

Base Information

• Chemical Name: 1,6-Anhydro-2-azido-2-deoxy-4-o-[(1,1-dimethylethyl)diphenylsilyl]-beta-D-glucopyranose3-acetate
• CAS No.: 850637-35-3
• Molecular Formula: C24H29N3O5Si
• Molecular Weight: 467.58966
• Mol file: 850637-35-3.mol

Synonyms:1,6-ANHYDRO-2-AZIDO-2-DEOXY-4-O-[(1,1-DIMETHYLETHYL)DIPHENYLSILYL]-BETA-D-GLUCOPYRANOSE3-ACETATE;

Chemical Property of 1,6-Anhydro-2-azido-2-deoxy-4-o-[(1,1-dimethylethyl)diphenylsilyl]-beta-D-glucopyranose3-acetate

Chemical Property:

• PSA: 103.74000
• LogP: 2.75006

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,6-Anhydro-2-azido-2-deoxy-4-o-[(1,1-dimethylethyl)diphenylsilyl]-beta-D-glucopyranose3-acetate

There total 3 articles about 1,6-Anhydro-2-azido-2-deoxy-4-o-[(1,1-dimethylethyl)diphenylsilyl]-beta-D-glucopyranose3-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,6-anhydro-2-azido-4-O-tertbutyldiphenylsilyl-2-deoxy-β-D-glucopyranose (115220-40-1) + acetic anhydride (108-24-7) → 3-O-acetyl-1,6-anhydro-2-azido-4-O-tert-butyldiphenylsilyl-2-deoxy-β-D-glucopyranose (850637-35-3)

Guidance literature:

With pyridine;

DOI:10.1021/ja045613g

Reference yield:

1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose (67546-20-7) → 3-O-acetyl-1,6-anhydro-2-azido-4-O-tert-butyldiphenylsilyl-2-deoxy-β-D-glucopyranose (850637-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: 2.75 g / pyridine

With pyridine;

DOI:10.1021/ja045613g

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → 3-O-acetyl-1,6-anhydro-2-azido-4-O-tert-butyldiphenylsilyl-2-deoxy-β-D-glucopyranose (850637-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: 2.75 g / pyridine

With pyridine;

DOI:10.1021/ja045613g

upstream raw materials:

1,6-anhydro-2-azido-4-O-tertbutyldiphenylsilyl-2-deoxy-β-D-glucopyranose

acetic anhydride

1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose

tert-butylchlorodiphenylsilane

Downstream raw materials:

3-O-acetyl-1,6-anhydro-2-azido-2-deoxy-β-D-glucopyranose