4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

Base Information

Chemical Name:4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide
CAS No.:134248-41-2
Molecular Formula:C₃₂H₂₃N₅O₃
Molecular Weight:525.566
Hs Code.:

4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

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Chemical Property of 4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

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Technology Process of 4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

There total 4 articles about 4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 90-02-8
salicylaldehyde

: 134248-34-3
4-<4,5-Dihydro-4-(1H-indol-3-ylmethylene)-5-oxo-2-phenyl-1H-imidazol-1-yl>benzoic acid hydrazide

: 134248-41-2
4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

Guidance literature:: With acetic acid; In ethanol; for 5h; Heating;

Reference yield:

: 42136-84-5,102913-26-8
for 3e

: 134248-41-2
4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / 0.33 h / 140 °C

2: 78 percent / 99percent N₂H₄*H₂O / ethanol / 8 h / Heating

3: 72 percent / glacial AcOH / ethanol / 5 h / Heating

With hydrazine hydrate; acetic acid; In ethanol;

Reference yield:

: 134248-30-9
Methyl 4-<4,5-dihydro-4-(1H-indol-3-ylmethylene)-5-oxo-2-phenyl-1H-imidazol-1-yl>benzoate

: 134248-41-2
4-{4-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-5-oxo-2-phenyl-4,5-dihydro-imidazol-1-yl}-benzoic acid [1-(2-hydroxy-phenyl)-meth-(Z)-ylidene]-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / 99percent N₂H₄*H₂O / ethanol / 8 h / Heating

2: 72 percent / glacial AcOH / ethanol / 5 h / Heating

With hydrazine hydrate; acetic acid; In ethanol;