14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile

Base Information

• Chemical Name: 14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile
• CAS No.: 74285-75-9
• Molecular Formula: C₂₀H₂₉NO
• Molecular Weight: 299.456
• Mol file: 74285-75-9.mol

Synonyms:

Chemical Property of 14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile

There total 3 articles about 14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9,14-dihydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-10,12-nonadiene-15-nitrile (102935-64-8) → 14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile (74285-75-9)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 0.05h; Yield given; Heating;

Reference yield:

9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-9,11-heptadien-13-one (51077-54-4) → 14-hydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-8,10,12-nonatriene-15-nitrile (74285-75-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaOH; 2.) KU-2 cation exchange resin H(+) form / 1.) DMF, toluene, 5-7 deg C, 1 h; 2.) acetonitrile, water, diethyl ether, 40 deg C, 40 min

2: p-toluenesulfonic acid / toluene / 0.05 h / Heating

With sodium hydroxide; KU-2 cation exchange resin H(+) form; toluene-4-sulfonic acid; In toluene;

Reference yield:

→ 1-Hydroxy-2,6-dimethyl-8-(2,6,6-trimethyl-cyclohexan-1-yl)-1-cyan-octatrien-2,4,6 (74285-75-9)

Guidance literature:

aus β-C-19-Aldehyd u. NaCN in MeOH, dann AcOH;

upstream raw materials:

9,14-dihydroxy-9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-10,12-nonadiene-15-nitrile

9,13-dimethyl-7-(1,1,5-trimethyl-5-cyclohexen-6-yl)-9,11-heptadien-13-one