3-nitro-2-propoxybenzoic acid

Base Information

• Chemical Name: 3-nitro-2-propoxybenzoic acid
• CAS No.: 75024-21-4
• Molecular Formula: C₁₀H₁₁NO₅
• Molecular Weight: 225.201
• Mol file: 75024-21-4.mol

Synonyms:NSC 37275

Chemical Property of 3-nitro-2-propoxybenzoic acid

Chemical Property:

• Vapor Pressure: 9.74E-07mmHg at 25°C
• Boiling Point: 388.7°C at 760 mmHg
• Flash Point: 188.9°C
• Density: 1.318g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-nitro-2-propoxybenzoic acid

There total 2 articles about 3-nitro-2-propoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-hydroxy-3-nitro-benzoic acid methyl ester (22621-41-6) + propyl bromide (106-94-5) → 3-nitro-2-propoxy-benzoic acid (75024-21-4)

Guidance literature:

With -base;

DOI:10.1021/ja01620a028

Reference yield:

propyl benzenesulfonate (80-42-2) + 3-nitrosalicylic acid (85-38-1) → 3-nitro-2-propoxy-benzoic acid (75024-21-4)

Guidance literature:

With potassium carbonate; xylene; Erwaermen des Reaktionsprodukts mit wss.-aethanol. NaOH;

Reference yield:

3-nitro-2-propoxy-benzoic acid (75024-21-4) → 3-amino-2-propoxy-benzoic acid-(2-diethylamino-ethyl ester) (108982-38-3)

Guidance literature:

Multi-step reaction with 2 steps

1: isopropyl alcohol

2: iron; aq.-ethanolic HCl

With hydrogenchloride; iron; isopropyl alcohol;

upstream raw materials:

propyl benzenesulfonate

3-nitrosalicylic acid

2-hydroxy-3-nitro-benzoic acid methyl ester

propyl bromide

Downstream raw materials:

3-nitro-2-propoxy-benzoic acid-(2-diethylamino-ethyl ester)

3-amino-2-propoxy-benzoic acid-(2-diethylamino-ethyl ester)