(E)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate

Base Information

• Chemical Name: (E)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate
• CAS No.: 1187438-54-5
• Molecular Formula: C₂₉H₃₄F₃NO₉
• Molecular Weight: 597.585
• Mol file: 1187438-54-5.mol

Synonyms:

Chemical Property of (E)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate

There total 1 articles about (E)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-allyl-2,3,3-tris-ethoxycarbonyl-hept-5-ynoic acid ethyl ester (864847-09-6) + p-trifluoromethyl-phenylisocyanate (1548-13-6) → (E)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate (1187438-54-5) + (Z)-tetraethyl 4-methylene-5-(1-oxo-1-(4-(trifluoromethyl)phenylamino)propan-2-ylidene)cyclohexane-1,1,2,2-tetracarboxylate (1187438-55-6)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; 1,3-bis(2,6-diisopropylphenyl)-1,3-dihydro-2H-imidazol-2-ylidene; In toluene; at 100 ℃; for 7h; optical yield given as %de; Inert atmosphere;

DOI:10.1021/ol901703t

upstream raw materials:

2-allyl-2,3,3-tris-ethoxycarbonyl-hept-5-ynoic acid ethyl ester

p-trifluoromethyl-phenylisocyanate