2-Bromothiazolo[5,4-c]pyridin-4(5H)-one

Base Information

Chemical Name:2-Bromothiazolo[5,4-c]pyridin-4(5H)-one
CAS No.:1035219-80-7
Molecular Formula:C6H3BrN2OS
Molecular Weight:231.073
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80702676
Wikidata:Q72512910
Mol file:1035219-80-7.mol

Synonyms:2-Bromothiazolo[5,4-c]pyridin-4(5H)-one;1035219-80-7;2-Bromo-thiazolo[5,4-c]pyridin-4(5H)-one;SCHEMBL2580463;DTXSID80702676;MFCD22571264;ZB0097;AKOS016012463;SY059299;CS-0187996;O10706;2-Bromo[1,3]thiazolo[5,4-c]pyridin-4(5H)-one;2-BROMO-5H-[1,3]THIAZOLO[5,4-C]PYRIDIN-4-ONE

Suppliers and Price of 2-Bromothiazolo[5,4-c]pyridin-4(5H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Bromothiazolo[5,4-c]pyridin-4(5H)-one 95+%
1g
$ 1250.00

American Custom Chemicals Corporation
2-BROMOTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE 95.00%
5MG
$ 499.22

Alichem
2-Bromothiazolo[5,4-c]pyridin-4(5H)-one
5g
$ 3551.00

Total 8 raw suppliers

Chemical Property of 2-Bromothiazolo[5,4-c]pyridin-4(5H)-one

Chemical Property:

Boiling Point:478.0±45.0 °C(Predicted)
PKA:10.75±0.20(Predicted)
PSA：74.25000
Density:1.910±0.06 g/cm3(Predicted)
LogP:2.15940
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:229.91495
Heavy Atom Count:11
Complexity:221

Purity/Quality:

95% purity ^*data from raw suppliers

2-Bromothiazolo[5,4-c]pyridin-4(5H)-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CNC(=O)C2=C1N=C(S2)Br

Technology Process of 2-Bromothiazolo[5,4-c]pyridin-4(5H)-one

There total 2 articles about 2-Bromothiazolo[5,4-c]pyridin-4(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 1035219-79-4
3-(2-bromothiazol-4-yl)acrylic acid

: 1035219-80-7
2-bromo-5H-thiazolo[5,4-c]pyridin-4-one

Guidance literature:: 3-(2-bromothiazol-4-yl)acrylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 2h;

With sodium azide; In 1,4-dioxane; water; acetone; at 0 ℃; for 1h;

In 1,4-dioxane; diphenyl ether-biphenyl eutectic; at 20 - 230 ℃;

Reference yield: 7.0%

: 108-05-4,9003-20-7
vinyl acetate

: 2-bromo-N-(pivaloyloxy)thiazole-5-carboxamide

: 1035219-80-7
2-bromo-5H-thiazolo[5,4-c]pyridin-4-one

Guidance literature:: With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; caesium carbonate; In methanol; at 45 ℃; for 60h; Inert atmosphere;

Reference yield: 80.0%

: 871829-90-2
(4-cyclopropoxyphenyl)boronic acid

: 1035219-80-7
2-bromo-5H-thiazolo[5,4-c]pyridin-4-one

: 1035219-81-8
2-(4-cyclopropoxyphenyl)-5H-thiazolo[5,4-c]pyridin-4-one

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; ethanol; water; at 85 ℃; for 18h;