Chemical Property of Cdppb
Chemical Property:
- Vapor Pressure:0mmHg at 25°C
- Boiling Point:523.277°C at 760 mmHg
- Flash Point:270.268°C
- PSA：70.71000
- Density:1.203g/cm3
- LogP:4.73628
- Storage Temp.:Store at +4°C
- Solubility.:DMSO: ≥5mg/mL at warmed to 60°C
- XLogP3:4.4
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:4
- Exact Mass:364.13241115
- Heavy Atom Count:28
- Complexity:572
- Purity/Quality:
-
98% *data from raw suppliers
CDPPB *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
22
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC=C(C=C1)C2=NN(C(=C2)NC(=O)C3=CC=CC(=C3)C#N)C4=CC=CC=C4
-
Uses
3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide is a glutamate metabotropic (mGluR5) positive allosteric modulator, used in the treatment of Phelan-McDermid syndrome caused by 22qI3 deletion. Studies have shown that 3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide suppresses the incre ase of LDH release and caspase-3 activation induced by traumatic neuronal injury. CDPPB may be used in mGluR5-mediated cell signaling studies.
