D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin

Base Information

• Chemical Name: D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin
• CAS No.: 1073243-67-0
• Molecular Formula: C₂₃H₃₃N₁₅O₁₄
• Molecular Weight: 743.607

Synonyms:

Chemical Property of D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin

Chemical Property:

Purity/Quality:

Safty Information:

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Useful:

Technology Process of D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin

There total 1 articles about D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2',2''',3,6'''-pentaazidoparornomycin (875125-33-0) → D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin (1073243-67-0)

Guidance literature:

With periodic acid; In tetrahydrofuran; at 0 ℃; for 3h; Molecular sieve; Inert atmosphere;

DOI:10.1002/hlca.200890167

Reference yield:

D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin (1073243-67-0) + aniline (62-53-3) → 1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)-4-O-(3,4,5-trideoxy-4-N-phenyl-4-aza-α-D-erythro-heptoseptanosyl)paromomycin (1073243-68-1)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; at 26 ℃; for 13h; Inert atmosphere;

DOI:10.1002/hlca.200890167

Reference yield:

D-glyceraldehyde-(2->1)-(1R)-2-azido-2-deoxy-D-glycerodialdehyde-(1->4)-1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)paromomycin (1073243-67-0) + benzylamine (100-46-9) → 1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)-4-O-(4-N-benzyl-3,4,5-trideoxy-4-aza-α-D-erythro-heptoseptanosyl)paromomycin (1073243-69-2)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; at 26 ℃; for 13h; Inert atmosphere;

DOI:10.1002/hlca.200890167

upstream raw materials:

1,2',2''',3,6'''-pentaazidoparornomycin

Downstream raw materials:

1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)-4-O-(3,4,5-trideoxy-4-N-phenyl-4-aza-α-D-erythro-heptoseptanosyl)paromomycin

1,3,2',6'-tetraazido-1,3,2',6'-tetradeamino-4-O-de(2-amino-2-deoxy-α-D-glucopyranosyl)-4-O-(4-N-benzyl-3,4,5-trideoxy-4-aza-α-D-erythro-heptoseptanosyl)paromomycin

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