6-Hydroxyisoindolin-1-one

Base Information

Chemical Name:6-Hydroxyisoindolin-1-one
CAS No.:659737-57-2
Molecular Formula:C8H7NO2
Molecular Weight:149.149
Hs Code.:2933790090
European Community (EC) Number:830-841-6
DSSTox Substance ID:DTXSID10468056
Nikkaji Number:J2.692.790K
Wikidata:Q82295152
Mol file:659737-57-2.mol

Synonyms:6-hydroxyisoindolin-1-one;659737-57-2;6-hydroxy-2,3-dihydroisoindol-1-one;6-HYDROXY-2,3-DIHYDRO-ISOINDOL-1-ONE;1H-Isoindol-1-one, 2,3-dihydro-6-hydroxy-;6-HYDROXY-2,3-DIHYDRO-1H-ISOINDOL-1-ONE;MFCD08276013;AM1124;2,3-Dihydro-6-hydroxy-1H-isoindol-1-one;SCHEMBL4499446;DTXSID10468056;YGEDYDDFFVHFEA-UHFFFAOYSA-N;AKOS006287665;DS-4207;MB06080;SY031207;FT-0703206;EN300-173614;Z1198177071

Suppliers and Price of 6-Hydroxyisoindolin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Hydroxyisoindolin-1-one
100mg
$ 265.00

Crysdot
6-Hydroxyisoindolin-1-one 95%
10g
$ 1817.00

Crysdot
6-Hydroxyisoindolin-1-one 95%
5g
$ 1089.00

Crysdot
6-Hydroxyisoindolin-1-one 95%
1g
$ 363.00

Chemenu
6-Hydroxyisoindolin-1-one 95%
1g
$ 343.00

Chemenu
6-Hydroxyisoindolin-1-one 95%
5g
$ 1029.00

Chemcia Scientific
6-Hydroxy-2,3-dihydro-isoindol-1-one 95%
5 G
$ 795.00

American Custom Chemicals Corporation
6-HYDROXYISOINDOLIN-1-ONE 95.00%
5MG
$ 503.75

Ambeed
6-Hydroxyisoindolin-1-one 95%
5g
$ 748.00

Ambeed
6-Hydroxyisoindolin-1-one 95%
1g
$ 224.00

Total 20 raw suppliers

Chemical Property of 6-Hydroxyisoindolin-1-one

Chemical Property:

Boiling Point:507.336 °C at 760 mmHg
PKA:9.43±0.20(Predicted)
Flash Point:260.628 °C
PSA：52.82000
Density:1.362 g/cm³
LogP:0.64600
Storage Temp.:2-8°C
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:149.047678466
Heavy Atom Count:11
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

6-Hydroxyisoindolin-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=C(C=C(C=C2)O)C(=O)N1

Technology Process of 6-Hydroxyisoindolin-1-one

There total 3 articles about 6-Hydroxyisoindolin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 22246-66-8,132680-54-7
6-methoxy-2,3-dihydro-isoindol-1-one

: 659737-57-2
6-hydroxy-2,3-dihydro-1H-isoindol-1-one

Guidance literature:: 6-methoxy-2,3-dihydro-isoindol-1-one; With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 18h;

With methanol; In dichloromethane; at -78 ℃; for 2h;

Reference yield:

: 788081-99-2
methyl 2-(bromomethyl)-5-methoxy-benzoate

: 659737-57-2
6-hydroxy-2,3-dihydro-1H-isoindol-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonia / methanol / 2 h / 125 °C

2.1: boron tribromide / dichloromethane / 4 h / 20 °C

2.2: pH 6.5

With ammonia; boron tribromide; In methanol; dichloromethane;

Reference yield:

: 73502-03-1
methyl 5-methoxy-2-methyl-benzoate

: 659737-57-2
6-hydroxy-2,3-dihydro-1H-isoindol-1-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile) / tetrachloromethane / 2 h / Heating / reflux

2.1: ammonia / methanol / 2 h / 125 °C

3.1: boron tribromide / dichloromethane / 4 h / 20 °C

3.2: pH 6.5

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); ammonia; boron tribromide; In methanol; tetrachloromethane; dichloromethane;