6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide

Base Information

• Chemical Name: 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide
• CAS No.: 371942-69-7
• Molecular Formula: C25H21N7O3
• Molecular Weight: 467.48
• DSSTox Substance ID: DTXSID90433303
• Nikkaji Number: J2.560.661B
• Wikidata: Q27163245
• ChEMBL ID: CHEMBL2178735
• Mol file: 371942-69-7.mol

Synonyms:6-amino-N-(3-(4-(4-morpholinyl)pyrido(3',2'-4,5)furo(3,2-d)pyrimidin-2-yl)phenyl)-3-pyridinecarboxamide;YM 201636;YM-201636;YM201636

Chemical Property of 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide

Chemical Property:

• PSA: 132.29000
• Density: 1.446
• LogP: 4.22330
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Very Slightly)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 4
• Exact Mass: 467.17058756
• Heavy Atom Count: 35
• Complexity: 738

Purity/Quality:

98%,99%, ^*data from raw suppliers

YM201636 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)NC(=O)C6=CN=C(C=C6)N
• Uses: YM 201636 is a phosphatidylinositol phosphate kinase PIP5KIII (PIKfyve) inhibitor and significantly reduces the survival of primary mouse hippocampal neurons in culture. YM-201636 treatment increases the level of the autophagosomal marker protein LC3-II.