2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride

Base Information

• Chemical Name: 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride
• CAS No.: 143265-03-6
• Molecular Formula: C₄₀H₄₆N₂O₃
• Molecular Weight: 602.817
• Mol file: 143265-03-6.mol

Synonyms:

Chemical Property of 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride

There total 7 articles about 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl isopropylidenesuccinate (42103-98-0) → 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride (143265-03-6,143423-89-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) lithium diisopropylamide / 1.) THF, hexane, -70 deg C, 30 min, 2.) THF, RT, 1 h

2: potassium hydroxide / ethanol / 3 h / Heating

3: acetic anhydride / Heating

With potassium hydroxide; acetic anhydride; lithium diisopropyl amide; In ethanol;

DOI:10.1246/bcsj.65.2352

Reference yield:

4-Diethylaminobenzaldehyde (120-21-8) → 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride (143265-03-6,143423-89-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 61 percent / sodium hydride / 1,2-dimethoxy-ethane / 0.5 h / 60 °C

2: 1.) BuLi / 1.) hexane, THF, -70 deg C, 20 min, 2.) THF, RT, 2 h

3: 1.) lithium diisopropylamide / 1.) THF, hexane, -70 deg C, 30 min, 2.) THF, RT, 1 h

4: potassium hydroxide / ethanol / 3 h / Heating

5: acetic anhydride / Heating

With potassium hydroxide; n-butyllithium; acetic anhydride; sodium hydride; lithium diisopropyl amide; In 1,2-dimethoxyethane; ethanol;

DOI:10.1246/bcsj.65.2352

Reference yield:

2-bromo-4,6-bis(O,O-diethylphosphonylmethyl)-m-xylene (174362-43-7) → 2-<2,6-dimethy-3,5-bis(p-diethylaminostyryl)benzylidene>-3-isopropylidenesuccinic anhydride (143265-03-6,143423-89-6)

Guidance literature:

Multi-step reaction with 5 steps

1: 61 percent / sodium hydride / 1,2-dimethoxy-ethane / 0.5 h / 60 °C

2: 1.) BuLi / 1.) hexane, THF, -70 deg C, 20 min, 2.) THF, RT, 2 h

3: 1.) lithium diisopropylamide / 1.) THF, hexane, -70 deg C, 30 min, 2.) THF, RT, 1 h

4: potassium hydroxide / ethanol / 3 h / Heating

5: acetic anhydride / Heating

With potassium hydroxide; n-butyllithium; acetic anhydride; sodium hydride; lithium diisopropyl amide; In 1,2-dimethoxyethane; ethanol;

DOI:10.1246/bcsj.65.2352

upstream raw materials:

diethyl isopropylidenesuccinate

4-Diethylaminobenzaldehyde

2-bromo-4,6-bis(O,O-diethylphosphonylmethyl)-m-xylene

2,6-dimethyl-3,5-bis(p-diethyaminostyryl)benzaldehyde